Diffusion tensor imaging: serial quantitation of white matter tract maturity in premature newborns

NeuroImage
Savannah C PartridgeD B Vigneron

Abstract

Magnetic resonance diffusion tensor imaging (DTI) enables the discrimination of white matter pathways before myelination is evident histologically or on conventional MRI. In this investigation, 14 premature neonates with no evidence of white matter abnormalities by conventional MRI were studied with DTI. A custom MR-compatible incubator with a novel high sensitivity neonatal head coil and improved acquisition and processing techniques were employed to increase image quality and spatial resolution. The technical improvements enabled tract-specific quantitative characterization of maturing white matter, including several association tracts and subcortical projection tracts not previously investigated in neonates by MR. Significant differences were identified between white matter pathways, with earlier maturing commissural tracts of the corpus callosum, and deep projection tracts of the cerebral peduncle and internal capsule exhibiting lower mean diffusivity (Dav) and higher fractional anisotropy (FA) than later maturing subcortical projection and association pathways. Maturational changes in white matter tracts included reductions in Dav and increases in FA with age due primarily to decreases in the two minor diffusion eigenvalue...Continue Reading

References

May 1, 1988·Journal of Neuropathology and Experimental Neurology·H C KinneyF H Gilles
Apr 1, 1985·Statistics in Medicine·J S Maritz
Oct 1, 1973·Archives of Disease in Childhood·J Dobbing, J Sands
Jan 1, 1995·Journal of Computer Assisted Tomography·D M WimbergerJ Kucharczyk
Aug 1, 1994·Neurochemical Research·H C KinneyD A Kirschner
Jun 1, 1996·Journal of Magnetic Resonance. Series B·P J Basser, C Pierpaoli
Feb 4, 1998·Journal of Computer Assisted Tomography·R P WoodsJ C Mazziotta
Feb 4, 1998·Journal of Computer Assisted Tomography·R P WoodsJ C Mazziotta
Sep 1, 1999·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S Pajevic, C Pierpaoli
Sep 1, 1999·Proceedings of the National Academy of Sciences of the United States of America·T E ConturoM E Raichle
Aug 5, 2000·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·A PfefferbaumM Moseley
Oct 12, 2000·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·P J BasserA Aldroubi
Jan 18, 2002·The New England Journal of Medicine·Maureen HackNancy Klein
Aug 8, 2002·Magnetic Resonance Imaging·Saïd BoujrafMichel Osteaux
Aug 10, 2002·JAMA : the Journal of the American Medical Association·Adnan T BhuttaK J S Anand
Nov 20, 2002·AJR. American Journal of Roentgenology·Peter McGrawJames M Provenzale
Nov 27, 2002·Journal of Magnetic Resonance Imaging : JMRI·Steven P MillerA James Barkovich
Feb 3, 2004·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Khader M HasanPonnada A Narayana

❮ Previous
Next ❯

Citations

Aug 15, 2013·Neuroradiology·Anand S PanditSerena J Counsell
Mar 14, 2012·Pediatric Radiology·Cédric Clouchoux, Catherine Limperopoulos
Mar 17, 2012·Pediatric Radiology·V LepomäkiUNKNOWN PIPARI Study Group
Aug 21, 2012·Pediatric Radiology·Kerstin PannekStephen E Rose
Jan 5, 2013·Pediatric Radiology·Shoko YoshidaSusumu Mori
Jun 25, 2013·Pediatric Radiology·Virva LepomäkiUNKNOWN PIPARI study group
Feb 24, 2009·Bulletin of Mathematical Biology·Daniel A Beard, Fan Wu
Apr 3, 2012·Neuroinformatics·Ferran PradosSalvador Pedraza
Apr 27, 2005·NeuroImage·Christopher D KroenkeJeffrey J Neil
Oct 6, 2009·Lancet Neurology·Laura R MentPetra S Hüppi
Dec 15, 2007·Journal of the International Neuropsychological Society : JINS·Jamie O EdginLianne J Woodward
Aug 4, 2012·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Xiujuan GengJohn H Gilmore
Nov 9, 2007·The New England Journal of Medicine·Steven P MillerDaniel B Vigneron
Nov 5, 2004·The New England Journal of Medicine·Donna M Ferriero
Apr 14, 2009·Cerebral Cortex·Christopher D KroenkePhilip V Bayly
Mar 20, 2010·Cerebral Cortex·Christopher D SmyserJeffrey J Neil
May 14, 2005·Neuroreport·Yong-Wook ShinJun Soo Kwon
Apr 7, 2007·Topics in Magnetic Resonance Imaging : TMRI·Michael J J KimMeng Law
Jul 19, 2012·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Marieke A HemelsFloris Groenendaal
Jul 4, 2007·Topics in Magnetic Resonance Imaging : TMRI·Ashok Panigrahy, Stefan Blüml
Dec 22, 2011·Topics in Magnetic Resonance Imaging : TMRI·Orit Glenn
Dec 22, 2011·Topics in Magnetic Resonance Imaging : TMRI·Terrie E InderJeffrey J Neil
Oct 25, 2011·PloS One·Matthew P G AllinChiara Nosarti
Apr 3, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Hao HuangSusumu Mori
Feb 8, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Hao HuangSusumu Mori
Feb 8, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Elizabeth R SowellSusan Y Bookheimer
Jul 25, 2007·AJR. American Journal of Roentgenology·James M ProvenzaleLeonard E White
Nov 26, 2010·AJR. American Journal of Roentgenology·James M ProvenzaleChunlei Liu
Apr 27, 2013·AJR. American Journal of Roentgenology·Efsun UrgerJames M Provenzale
Jun 26, 2013·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Hao Huang, Lana Vasung
Feb 1, 2014·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·XiaoLin MiaoYanNi Jiang
Apr 25, 2012·Annals of Pediatric Cardiology·Moustafa M Abdel Raheem, Walid A Mohamed
Apr 10, 2012·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Michela GroppoA David Edwards

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