Diffusion tensor magnetic resonance imaging of the normal breast: reproducibility of DTI-derived fractional anisotropy and apparent diffusion coefficient at 3.0 T.

La Radiologia medica
Alberto TagliaficoMassimo Calabrese

Abstract

Diffusion-weighted imaging (DWI) may improve the diagnostic performance of conventional breast magnetic resonance imaging (MRI). Diffusion tensor imaging (DTI) is an extension of DWI. If DTI-derived measurements are to be clinically useful, particularly for predicting and/or monitoring therapeutic effects, they must be robust and reliable. The purpose of this study was to assess intra- and interobserver reproducibility of DTI-derived fractional anisotropy (FA) and apparent diffusion coefficient (ADC) at 3.0 T. This prospective study was approved by the Institutional Review Board, and participants provided written informed consent. Sixty normal contralateral breasts of 60 patients (28-85 years, median 57) were analysed with a DWI sequence following a standard MRI protocol. Four authors performed all postprocessing and analyses independently and in different sessions. The same authors, blinded to the initial results, repeated the image postprocessing and analysis 4 weeks after the initial session. Mean ADC and FA for DTI sequences were, respectively, 1.92±0.30 and 0.32±0.09. Intra- and interobserver agreement of the four radiologists for ADC and FA were good (acceptable). Kappa values for ADC were intra-R1=0.82; intra-R2=0.84; in...Continue Reading

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Citations

Jun 4, 2014·PloS One·Alberto TagliaficoMassimo Calabrese
Feb 19, 2014·Radiology·Noam NissanHadassa Degani
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Jul 28, 2016·The British Journal of Radiology·Ángela BernabeuJavier Sánchez-González
Oct 1, 2016·Journal of Magnetic Resonance Imaging : JMRI·Savannah C PartridgeEric E Sigmund
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Sep 15, 2019·Journal of Magnetic Resonance Imaging : JMRI·Mami IimaKaori Togashi
Sep 24, 2016·Journal of Magnetic Resonance Imaging : JMRI·Can OnaygilErkin Aribal
Apr 21, 2016·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Ruisheng JiangXiming Wang
Jun 2, 2020·Frontiers in Medicine·Apekshya ChhetriJoseph V Rispoli

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