PMID: 9630194Jun 18, 1998Paper

Diffusion-weighted magnetic resonance and magnetization transfer imaging in the assessment of ischemic human stroke

Internal Medicine
H HanyuK Abe

Abstract

We compared characteristic features in ischemic stroke lesions from the hyperacute to the chronic stage on diffusion-weighted (DW) and magnetization transfer (MT) images with those on T2-weighted (T2W) images, and assessed changes in apparent diffusion coefficient (ADC), MT effect (MTe), and T2 ratios (infarct/normal) over time. DW images were particularly useful for detecting hyperacute infarcts within 6 hours of onset and in distinguishing acute lesions from chronic lesions. ADC ratios were lower within 7 days after onset and rose toward 1.0 in the subacute phase, becoming relatively isotense on ADC maps, but elevated thereafter. Although MTe ratios were unchanged or only subtly changed in the acute stage, they became significantly lower in the subacute and chronic stages. These combined magnetic resonance (MR) techniques were useful in the assessment of ischemic stroke and facilitated the determination of the age of cerebral infarct.

Citations

Jun 30, 2007·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Massimo Filippi, Maria A Rocca
Jan 16, 2002·Journal of the Neurological Sciences·Hiromitsu NakaShigenobu Nakamura
Sep 4, 1999·Journal of the Neurological Sciences·H HanyuK Abe
Apr 22, 2015·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·I SibonV Dousset
May 29, 2008·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Ursula I TuorBoguslaw Tomanek

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