Diffusion-weighted magnetic resonance imaging in Wernicke's encephalopathy

Acta Neurologica Scandinavica
K S HongG Hur

Abstract

To report diffusion-weighted imaging (DWI) findings and postulate the pathogenic mechanism of Wernicke's encephalopathy (WE). A 47-year-old-woman presented with altered consciousness, ophthalmoplegia, and ataxia. DWI revealed the abnormal signal changes in periaqueductal gray matter, mamillary bodies and bilateral medial thalami. Apparent diffusion coefficient (ADC) map revealed the high signal intensity lesions in bilateral medial thalami, suggestive of vasogenic edema. The abnormal signal intensity lesions disappeared on follow-up imaging with clinical improvement. Vasogenic edema plays an important role in the pathogenesis of WE and can be reversed by proper management. DWI findings in the early stage of WE may provide useful information about the prognosis.

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Citations

May 31, 2006·Journal of Neuroradiology. Journal De Neuroradiologie·B LapergueP Amarenco
Jan 29, 2014·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Seungyoo KimJoong-Seok Kim
Jul 23, 2014·BioMed Research International·Gaetana ManzoAndrea Manto
May 22, 2007·Journal of the Neurological Sciences·Rainer SurgesMichel Rijntjes
Jun 24, 2004·Journal of the American Geriatrics Society·Leonetto GiglioliMarco Mannucci
Mar 7, 2008·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Satyakam BhagavatiJai Choi
Feb 28, 2003·Neurology·M BerguiJ Zhong
Dec 3, 2010·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Bhagheerathi KalidassRajesh Paraswani
Nov 26, 2009·Neurologic Clinics·Neeraj Kumar

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