PMID: 29097884Jul 1, 2016Paper

Diffusion weighted MRI and spectroscopy in invasive carcinoma of the breast at 3Tesla. Correlation with dynamic contrast enhancement and pathologic findings

Hippokratia
G BoulogianniA Drevelegas

Abstract

The most common histological types of invasive breast carcinomas are the invasive ductal carcinoma (IDC) and the invasive lobular carcinoma (ILC). The purpose of our study was to evaluate the role of the diffusion-weighted imaging (DWI) and the in vivo proton magnetic resonance spectroscopy ((1)H-MRS ) at 3 Tesla magnet in invasive breast cancer and correlate them with the dynamic contrast enhancement (DCE) and pathologic findings. We retrospectively studied at 3Tesla magnet the apparent diffusion coefficient (ADC) values, the detection of choline in the (1)H-MRS and the kinetic analyses obtained after DCE in 181 patients with histologically confirmed invasive breast carcinomas. Among these patients, 160 had IDC and 21 ILC. We used the DWI sequence with a b value of 1,000 mm(2)/sec for the calculation of the ADC value, the fat-suppressed point-resolved spectroscopy (PRESS) sequence in order to evaluate the existence of a choline peak in the spectrum and the T1W GRE FAT SAT VIBRANT sequence for the characterization of the kinetic curves. Finally, we correlated the pathologic type of invasive cancer, as well as the type of the kinetic curve with the ADC value and the detectability of choline resonance in the spectrum in each of t...Continue Reading

Related Concepts

Related Feeds

Breast Invasive Carcinoma (Keystone)

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.

Carcinoma, Ductal

Ductal carcinoma is a malignant neoplasm involving the ductal systems of any of a number of organs, such as the mammary glands, pancreas, prostate or lacrimal gland. Discover the latest research on ductal carcinoma here.

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Breast Invasive Carcinoma

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.

Carcinoma, Lobular

Lobular carcinoma is an invasive type of breast cancer in which lobules, areas of the breast that produce milk, undergo malignant transformation. Here is the latest research.