Diffusion-weighted MRI as an adjunct to mammography in women under 50 years of age: an initial study

Journal of Magnetic Resonance Imaging : JMRI
Toshiki KazamaHideyuki Takano

Abstract

To evaluate diffusion-weighted magnetic resonance (DW) imaging as an adjunct to mammography for the detection of small invasive breast cancer. Institutional review board standards were followed for this retrospective study. We performed both breast DW imaging and mammography on 25 women under 50 years of age with pathologically proven T1 breast cancer and on 21 healthy women under 50 years of age. Four offsite radiologists blind to the clinical information independently interpreted the mammograms and DW images and then classified their confidence level regarding the presence of breast cancer. The composite area under receiver operating characteristic curve (AUC), of mammography alone, DW imaging alone, and the combination of DW imaging and mammography (DWI/Cal) were calculated. The AUC of composite ROC curves of mammography, DW imaging, DWI/Cal combination, was 0.79 (95% CI, 0.72-0.87), 0.86 (95% CI, 0.84-0.87), and 0.96 (95% CI, 0.92-1.00), respectively. DW imaging may be a useful adjunct to mammography in the detection of small invasive breast cancer in women under 50 years of age.

References

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Citations

Jun 13, 2013·European Journal of Radiology·Reiko WoodhamsYusuke Inoue
Aug 21, 2013·Journal of Magnetic Resonance Imaging : JMRI·Rajpaul Attariwala, Wayne Picker
Oct 1, 2016·Journal of Magnetic Resonance Imaging : JMRI·Savannah C PartridgeEric E Sigmund
Oct 9, 2019·Radiology·Nita AmornsiripanitchSavannah C Partridge
Sep 10, 2020·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Su Hyun LeeWoo Kyung Moon
Aug 7, 2020·AJR. American Journal of Roentgenology·Ramya PhamDonna Plecha
Nov 11, 2020·Journal of Magnetic Resonance Imaging : JMRI·Sung Eun SongWoo Kyung Moon
Nov 10, 2017·Clinical Imaging·Nita AmornsiripanitchSavannah C Partridge

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