DIGGING DESIGNER GENOMES

BioTechniques
Sarah A Webb

Abstract

Techniques such as Gibson and Golden Gate assembly and homologous recombination in yeast allow researchers to assemble DNA sequences millions of base pairs in length. Sarah Webb investigates the challenges of constructing designer chromosomes and genomes, and their potential applications.

References

May 22, 2010·Science·Daniel G GibsonJ Craig Venter
Mar 29, 2014·Science·Narayana AnnaluruSrinivasan Chandrasegaran

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Software Mentioned

BioXp
JCVI

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