Digital Breast Tomosynthesis and Synthetic 2D Mammography versus Digital Mammography: Evaluation in a Population-based Screening Program

Radiology
Solveig HofvindPer Skaane

Abstract

Purpose To compare the performance of digital breast tomosynthesis (DBT) and two-dimensional synthetic mammography (SM) with that of digital mammography (DM) in a population-based mammographic screening program. Materials and Methods In this prospective cohort study, data from 37 185 women screened with DBT and SM and from 61 742 women screened with DM as part of a population-based screening program in 2014 and 2015 were included. Early performance measures, including recall rate due to abnormal mammographic findings, rate of screen-detected breast cancer, positive predictive value of recall, positive predictive value of needle biopsy, histopathologic type, tumor size, tumor grade, lymph node involvement, hormonal status, Ki-67 level, and human epidermal growth factor receptor 2 status were compared in women who underwent DBT and SM screening and in those who underwent DM screening by using χ2 tests, two-sample unpaired t tests, and tests of proportions. Results Recall rates were 3.4% for DBT and SM screening and 3.3% for DM screening (P = .563). DBT and SM screening showed a significantly higher rate of screen-detected cancer compared with DM screening (9.4 vs 6.1 cancers per 1000 patients screened, respectively; P < .001). Th...Continue Reading

References

Jan 25, 2012·Breast Cancer Research and Treatment·Daniela BernardiNehmat Houssami
May 25, 2013·AJR. American Journal of Roentgenology·Stephen L RoseRussell Sexton
Aug 7, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A GoldhirschUNKNOWN Panel members
Jul 25, 2014·JAMA : the Journal of the American Medical Association·Sarah M FriedewaldEmily F Conant
Oct 22, 2014·JAMA : the Journal of the American Medical Association·Sarah M FriedewaldEmily F Conant
Mar 18, 2015·JAMA : the Journal of the American Medical Association·Joann G ElmoreDonald L Weaver
Dec 29, 2015·Clinical Radiology·Fiona J GilbertKen C Young
Feb 20, 2016·JAMA Oncology·Nehmat Houssami, Diana L Miglioretti
May 24, 2016·The Breast : Official Journal of the European Society of Mastology·Robert HodgsonJulie Glanville

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Citations

Aug 29, 2018·Medical Physics·Marco CaballoIoannis Sechopoulos
Nov 30, 2018·The British Journal of Radiology·Sadia ChoudheryKathy Brandt
Jun 25, 2019·Journal of the National Cancer Institute·Carolina Rossi SaccarelliElizabeth A Morris
Nov 26, 2019·Annals of Internal Medicine·Holger J SchünemannUNKNOWN European Commission Initiative on Breast Cancer (ECIBC) Contributor Group
Jul 16, 2020·The British Journal of Radiology·Sadia Choudhery, Tara Anderson
Jan 27, 2019·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Joao V HorvatVictoria L Mango
May 16, 2019·Radiology·Alice ChongEmily F Conant
Aug 6, 2019·Annals of Saudi Medicine·Khawaja Bilal WaheedZechriah Jebakumar Arulanatham
Aug 7, 2020·AJR. American Journal of Roentgenology·Sadia ChoudheryRobert T Fazzio
Feb 6, 2021·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Yiming GaoSamantha L Heller
Jan 16, 2021·Medical & Biological Engineering & Computing·Maxine TanKwan Hoong Ng
Mar 12, 2021·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Nehmat HoussamiSolveig Hofvind
Mar 11, 2021·Current Biology : CB·Jeremy M Wolfe
Sep 24, 2020·AJR. American Journal of Roentgenology·Sadia ChoudheryTara Anderson
Jul 31, 2021·The Breast : Official Journal of the European Society of Mastology·Baoqi ZengQingxin Zhou
Aug 31, 2021·Journal of Imaging·Ana M MotaNuno Matela

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