Digital Compared with Screen-Film Mammography: Measures of Diagnostic Accuracy among Women Screened in the Ontario Breast Screening Program

Radiology
Maegan V PrummelAnna M Chiarelli

Abstract

To compare measures of diagnostic accuracy between large concurrent cohorts of women screened with digital computed radiography (CR), direct radiography (DR), and screen-film mammography (SFM). This study was approved by the University of Toronto Research Ethics Board; informed consent was not required. Three concurrent cohorts of women aged 50-74 years who were screened from 2008-2009 in the Ontario Breast Screening Program with SFM (487,334 screening examinations, 403,688 women), DR (254,758 screening examinations, 220,520 women), or CR (74,140 screening examinations, 64,210 women) were followed for 2 years or until breast cancer diagnosis. Breast cancers were classified as screening-detected or interval on the basis of the woman's final screening and assessment results. Interval cancer rate (per 10 000 negative screening examinations), sensitivity, and specificity were compared across the cohorts by using mixed-effects logistic regression analysis. Interval cancer rates were higher, although not significantly so, for CR (15.2 per 10,000; 95% confidence interval [CI]: 12.8, 17.8) and were similar for DR (13.7 per 10,000; 95% CI: 12.4, 15.0) compared with SFM (13.0 per 10,000; 95% CI: 12.1, 13.9). For CR versus SFM, specificit...Continue Reading

References

May 4, 2000·Journal of the National Cancer Institute·F D GillilandC R Key
Sep 20, 2005·The New England Journal of Medicine·Etta D PisanoUNKNOWN Digital Mammographic Imaging Screening Trial (DMIST) Investigators Group
Sep 22, 2007·AJR. American Journal of Roentgenology·Marco Rosselli Del TurcoNehmat Houssami
Nov 19, 2009·Annals of Internal Medicine·Heidi D NelsonUNKNOWN U.S. Preventive Services Task Force
Oct 19, 2011·Annals of Internal Medicine·Karla KerlikowskeUNKNOWN Breast Cancer Surveillance Consortium
Nov 23, 2011·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Marcello TonelliUNKNOWN Canadian Task Force on Preventive Health Care
Mar 16, 2013·The Breast : Official Journal of the European Society of Mastology·Fabiano H SouzaCarisi A Polanczyk
Jul 23, 2013·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Paula A van LuijtUNKNOWN National Evaluation Team for Breast Cancer Screening in Netherlands Study Group (NETB)
Aug 12, 2014·Breast Cancer Research and Treatment·Maegan V PrummelAnna M Chiarelli
Aug 20, 2014·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Jennifer I PayneRyan Duggan

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Citations

Jul 16, 2016·The Breast : Official Journal of the European Society of Mastology·Katharina HollandNico Karssemeijer
Nov 18, 2016·Insights Into Imaging·Francesco SardanelliUNKNOWN European Society of Breast Imaging (EUSOBI), with language review by Europa Donna–The European Breast Cancer Coalition
Dec 1, 2017·Breast Cancer Research : BCR·Katharina HollandNico Karssemeijer
Jun 24, 2020·Journal of the National Cancer Institute·Rachel FarberKaty Bell
Feb 6, 2017·Breast Cancer Research and Treatment·Katharina HollandNico Karssemeijer
Feb 24, 2017·Physics in Medicine and Biology·Katharina HollandNico Karssemeijer
May 4, 2018·Breast Cancer Research : BCR·Johanna O P WandersMartin Lillholm
Oct 10, 2018·AJR. American Journal of Roentgenology·Ying ChenConstance D Lehman

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