Digital Gangrene an Unusual Presentation of Takayasu's Arteritis

North American Journal of Medical Sciences
Manoj Kumar RoyPranab Maity

Abstract

Takayasu arteritis (TA) is a chronic inflammatory disease involving large vessels like aorta and its major branches. It presents to clinician with features of arm claudication, stroke, asymmetrical pulse, or asymmetrical blood pressure in both limbs. Digital gangrene may be occurred secondary to various systemic diseases like diabetes, thrombophilic states, vascular embolism, and medium and small vessel vasculitis or infections. Through evaluation to diagnose the exact etiology and timely intervention is needed to prevent progression of the gangrene which at the time can be life-threatening. Digital gangrene as an initial presentation in TA is very rare. In medical literature, there are only few case reports have been reported. We are reporting a case of a 26-year-old female patient presented with right little finger and index finger gangrene, ultimately diagnosed as TA and responded dramatically to treatment. Though rare, TA should be taken in the differential diagnosis for work up in a case of digital gangrene and it necessitates more studies in this field to uncover the exact pathophysiology for such presentation.

References

Apr 1, 1982·American Journal of Surgery·W M AbbottL S Wirthlin
Aug 1, 1997·International Journal of Cardiology·A HataF Numano
Jan 15, 2013·BMJ Case Reports·Sudhir VermaShailesh Singh

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Citations

Nov 14, 2015·Rheumatology International·Durga Prasanna MisraVikas Agarwal
Apr 16, 2021·Case Reports in Plastic Surgery & Hand Surgery·Alain J AzziPeter G Davison

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Methods Mentioned

BETA
antibody assay

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