Digital health revolution: perfect storm or perfect opportunity for pharmaceutical R&D?

Drug Discovery Today
Nick HirdHiroaki Kitano

Abstract

The convergence of technology and medicine has pushed healthcare to the brink of a major disruption that pharma has, until recently, been slow to recognize. Tech players have pioneered the emerging field of digital wellness and health, and pharma is ideally placed to use its expertise in drug development and embrace these technologies to create digital applications that address major medical needs. This review describes digital innovation from a pharma R&D perspective, outlining principal drivers, digital components, opportunities and challenges as well as a sustainable new business model predicated on empowered patients and achieving therapeutic outcomes.

References

Oct 25, 2006·Nature Cell Biology·Bree B AldridgePeter K Sorger
Nov 4, 2011·Nature Reviews. Genetics·Samik GhoshHiroaki Kitano
Nov 8, 2011·Annual Review of Medicine·Gari D Clifford, David Clifton
Mar 16, 2012·JAMA : the Journal of the American Medical Association·Donald M Berwick, Andrew D Hackbarth
Apr 25, 2012·Annual Review of Biomedical Engineering·Dae-Hyeong KimJohn A Rogers
Aug 8, 2012·Journal of Affective Disorders·Christopher BurtonMaria Wolters
Aug 31, 2012·The New England Journal of Medicine·Farshad Fani Marvasti, Randall S Stafford
Nov 6, 2012·Artificial Intelligence in Medicine·Marie ChanEric Campo
Apr 10, 2013·Journal of Diabetes Science and Technology·M Jason Brooke, Bradley Merrill Thompson
Dec 10, 2013·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Maria-Jose Santana, David Feeny
Feb 14, 2014·Nature·W Wayt Gibbs
Mar 26, 2014·Parkinsonism & Related Disorders·Dustin A HeldmanJoseph P Giuffrida
Apr 1, 2014·Psychiatry Research·Maria Faurholt-JepsenLars Vedel Kessing
Jul 24, 2014·The New England Journal of Medicine·Nathan G CortezAaron S Kesselheim
Aug 15, 2014·Current Medical Research and Opinion·Geoff AppelboomEmmanuel P L Dumont
Sep 24, 2014·Journal of Aging and Health·Ying-Yu ChaoCarolyn A Montgomery
Oct 15, 2014·Current Psychiatry Reports·H Lynn Horne-MoyerElizabeth S Messer
Dec 3, 2014·The American Journal of Medicine·Richard V Milani, Carl J Lavie
Jan 31, 2015·The New England Journal of Medicine·Francis S Collins, Harold Varmus
Feb 26, 2015·Lancet·Naomi Lee
Mar 31, 2015·Parkinsonism & Related Disorders·S AroraM A Little
Apr 19, 2015·BMC Medicine·Emil ChiauzziPronabesh DasMahapatra
Apr 24, 2015·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·James M Parish
May 1, 2015·Nature·Nicholas J Schork
May 8, 2015·Nature Reviews. Genetics·Maxwell W Libbrecht, William Stafford Noble
May 13, 2015·Nature Biotechnology·Eric ElenkoDaphne Zohar
May 13, 2015·Nature Biotechnology·Sachin H JainJohn S Brownstein
May 29, 2015·Nature·Tanguy Chouard, Liesbeth Venema
Jul 15, 2015·Nature Biotechnology·Eric ElenkoDaphne Zohar
Jul 17, 2015·Journal of Medical Internet Research·Sohrab SaebDavid C Mohr
Aug 1, 2015·Perspectives in Clinical Research·Neha Shankar Sharma
Sep 4, 2015·Nature·Kat Austen
Sep 5, 2015·Cell Systems·Kenneth D MandlIsaac S Kohane
Sep 9, 2015·Nature Biotechnology·David SteinbergDaphne Zohar
Oct 9, 2015·Nature Biotechnology·Michael Eisenstein
Dec 15, 2015·Science·Kelly Servick
Jun 28, 2016·The Behavior Analyst·Jesse DalleryPhilip Erb

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Citations

Jan 30, 2018·Clinical Pharmacology and Therapeutics·Oleksandr SverdlovTricia Thornton-Wells
Jan 20, 2017·Scientific Reports·Jonathan D YuenDavid A Stenger
Apr 2, 2020·American Journal of Lifestyle Medicine·Anne KuwabaraJeffrey Krauss
Jan 1, 2017·The Public Policy and Aging Report·Jeffrey Kaye

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