Dilated cardiomyopathy in 151 Irish Wolfhounds: Characteristic clinical findings, life expectancy and causes of death

The Veterinary Journal
C VollmarB Kohn

Abstract

Dilated cardiomyopathy (DCM) is an important cause of morbidity in Irish Wolfhounds (IW), a breed also predisposed to neoplastic and orthopedic diseases that shorten life expectancy. The objective of this study was to investigate survival and causes of death in IW with DCM and to characterise the clinical findings of DCM over time. Data from cardiovascular examinations performed in 1591 IW, including echocardiography and electrocardiography, were retrospectively evaluated. IW with DCM on medical therapy with long term longitudinal follow-up were included in this study (n=151; 95 males, 56 females). Based on their clinical status at initial diagnosis, IW were classified into one of three groups: preclinical DCM with sinus rhythm (PC-DCM-SR, n=35), preclinical DCM with atrial fibrillation (PC-DCM-AF, n=87), and congestive heart failure with DCM and AF (CHF-DCM-AF, n=29). Survival data were analyzed using cumulative incidence functions, Kaplan-Meier and Cox regression. CHF was predominantly characterized by chylous pleural and mild pericardial effusions. Causes of death were cardiac (CD) in 73/151 and non-cardiac (non-CD) in 62/151; 16 dogs remained alive at study end. The majority of deaths in both preclinical DCM groups were non...Continue Reading

Citations

Mar 1, 2020·Journal of Veterinary Internal Medicine·William D TyrrellFrances Abrams
Jul 18, 2020·Veterinary Surgery : VS·Logan M ScheuermannAndré J Nault
Aug 9, 2020·Journal of Veterinary Internal Medicine·Marco Baron ToaldoCarlo Guglielmini
Jun 17, 2020·Journal of Animal Science·Sydney R McCauleyEva M Oxford
Dec 22, 2020·Journal of Veterinary Internal Medicine·Kimberly J FreidVicky K Yang
Mar 21, 2021·Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology·Ashley L WalkerDarcy B Adin
Jul 15, 2021·Canine Medicine and Genetics·D B AdinK M Meurs

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