Dilemma of Environmental Health Research

Nihon eiseigaku zasshi. Japanese journal of hygiene
Katsuyuki MurataKanae Karita

Abstract

This article presents not only a brief overview of birth cohort studies focusing on environmental health in which the associations between health and environment were examined, but also a tentative plan to apply epidemiological data to benchmark dose calculation. According to the preceding studies, the checkpoints to be scrutinized when a result is not consistent with those of other researchers are as follows: (1) whether the study included all crucial confounders, (2) whether it included any exposure marker or confounder with a U-shaped dose-response curve, (3) whether the outcome measure was conducted by two or more examiners that might lead to measurement bias, (4) whether such examiners picked up information about exposure levels of the subjects before measuring the endpoints, and (5) whether subjects with different genetic factors were included in the analysis. In addition, (6) researchers conducting a children's study on developmental effects due to toxic substances must keep in mind that the impact of prenatal methylmercury exposure, independent of postnatal exposure, may continue for at least seven years. (7) When an environmental health research emphasizes to be population-based study, the levels of exposure to environ...Continue Reading

References

Aug 25, 1988·The New England Journal of Medicine·A J McMichaelR J Roberts
Oct 1, 1984·Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology·K S Crump
Dec 11, 1997·Neurotoxicology and Teratology·P GrandjeanP J Jørgensen
Feb 5, 2004·The Journal of Pediatrics·Philippe GrandjeanPál Weihe
Feb 5, 2004·The Journal of Pediatrics·Katsuyuki MurataPhilippe Grandjean
Jan 6, 2006·Environmental Health Perspectives·Gail A WassermanJoseph H Graziano
Feb 24, 2006·Risk Analysis : an Official Publication of the Society for Risk Analysis·Miwako DakeishiToyoto Iwata
Feb 25, 2006·The Tohoku Journal of Experimental Medicine·Mari SampeiDonald C Wood
May 2, 2006·Neurotoxicology and Teratology·Frodi DebesPhilippe Grandjean
Jul 19, 2006·Biomedical Research·Mari SampeiKatsuyuki Murata
Oct 28, 2006·Neurotoxicology and Teratology·Frodi DebesPhilippe Grandjean
Feb 22, 2008·Environmental Health Perspectives·Todd A JuskoRichard L Canfield
Jul 19, 2008·Stroke; a Journal of Cerebral Circulation·Jiu-Chiuan ChenMarcia L Stefanick
Jan 15, 2014·BMC Public Health·Toshihiro KawamotoUNKNOWN Working Group of the Epidemiological Research for Children’s Environmental Health
Oct 17, 2015·The Science of the Total Environment·Houman GoudarziReiko Kishi
Aug 25, 2016·Journal of Exposure Science & Environmental Epidemiology·Sachiko KobayashiReiko Kishi
Apr 23, 2017·The Science of the Total Environment·Nozomi TatsutaKatsuyuki Murata
May 10, 2017·The Tohoku Journal of Experimental Medicine·Nozomi TatsutaKunihiko Nakai
Jan 24, 2017·EFSA Journal·UNKNOWN EFSA Scientific CommitteeJosef R Schlatter

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved