PMID: 6413090Aug 1, 1983Paper

Dimethyl sulphoxide (DMSO) induced serum hyperosmolality

Clinical Biochemistry
P Wolf, M Simon

Abstract

We describe a patient who received intravenous dimethyl sulphoxide (DMSO) (as part of an experimental protocol) to control increased intracranial pressure. The patient died of a brain abscess. She developed extreme serum hyperosmolality from the DMSO with the osmolality peaking at 717 mosmol/kg. DMSO may induce extreme serum hyperosmolality and should be utilized cautiously.

References

Jun 3, 1971·The New England Journal of Medicine·A G Robinson, J N Loeb

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Citations

Aug 1, 1986·Journal of Neurology, Neurosurgery, and Psychiatry·I R Gunn, C Acomb
Nov 10, 2010·Journal of Pharmacological and Toxicological Methods·Carolina Sanmartín-SuárezEstefanía Méndez-Álvarez
Apr 24, 2004·Obstetrical & Gynecological Survey·Joseph R WaxAngelina Cartin

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