PMID: 8951419Dec 1, 1996Paper

Diminished plasma levels of vitamin E in patients with severe viral hepatitis

Free Radical Research
A von HerbayH Sies

Abstract

RRR-alpha-Tocopherol (Vitamin E) was assayed in plasma of 48 patients with viral hepatitis and of 32 healthy controls. In patients with highly elevated serum transaminases (ALT > 100 U/L) vitamin E plasma levels were significantly lower (17.5 +/- 4.8 mumol/L) than in controls (22.7 +/- 4.2 mumol/L, p < 0.01). The vitamin E/lipid ratios (3.12 +/- 0.63 mumol/g) in these patients were 33% lower than those of the controls (4.68 +/- 0.54 mumol/g). The lowered vitamin E levels in patients with acute or chronic viral hepatitis with high activity of disease may be due to free radical-mediated liver injury.

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Citations

Jun 5, 2002·Journal of Hepatology·Sanjiv K JainThomas W Warnes
Aug 6, 2005·Journal of Clinical Gastroenterology·Alla MelhemYaron Ilan
Oct 16, 2007·Journal of Nutritional Science and Vitaminology·Asako TakenakaKiharu Igarashi
Dec 17, 2008·World Journal of Gastroenterology : WJG·Patrick GernerStefan Wirth
Sep 3, 2014·Antioxidants & Redox Signaling·Dean P Jones, Rafael Radi
May 25, 2005·Liver International : Official Journal of the International Association for the Study of the Liver·Priyanka BandaraGeoffrey C Farrell
Sep 19, 2007·Pediatrics International : Official Journal of the Japan Pediatric Society·Bunyamin DikiciAydin Ece
Mar 9, 2002·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Robert A DisilvestroHaeyun G Lee
Jun 24, 1998·Biochemical and Biophysical Research Communications·Y YamamotoT Yoshikawa
Jun 23, 2016·Liver International : Official Journal of the International Association for the Study of the Liver·Sirio FiorinoPietro Andreone
Oct 19, 2002·The American Journal of Gastroenterology·Dhiraj YadavC S Pitchumoni
Oct 13, 2006·World Journal of Gastroenterology : WJG·Mustafa CemekNihat Mert
Jan 27, 1999·Metabolism: Clinical and Experimental·M P LookT Sauerbruch
Aug 28, 2021·Antioxidants·Stela DragomanovaLyubka Tancheva

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