PMID: 11926558Apr 3, 2002Paper

Diminutive polyps of large bowel should be an early target for endoscopic treatment

Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
A N KapsoritakisE A Kouroumalis

Abstract

Aim of the present study is to ascertain the importance of diminutive colorectal polyps and define the need for removal according to their characteristics and malignant potential. A total of 4,723 patients who underwent colonoscopy were evaluated and 624 patients with 826 polyps were recorded. There were 352 patients with 443 diminutive polyps, studied according to their distribution. Of these, 371 were removed, histologically examined and correlated to patient characteristics and occurrence of synchronous neoplasms. Of the right colon polyps, 81/115 were diminutive, versus 362/711 of the left colon (p<0.0001). Adenomas were more common in patients over 50 years of age, (p<0.0001). In all colonic segments, diminutive adenomas prevailed over hyperplastic polyps, whereas the proportion of diminutive adenomas predominated in the right colon (p=0.0015). Adenomas were classified as tubular 39%, tubulovillous 55.7% and villous 5.3%. The degree of dysplasia was mild in 45.5%, moderate in 51% and severe in 3.5%. The prevalence of synchronous neoplasms was 37.4%. They were more frequently found in males over 50 years of age and in patients with diminutive adenomas compared to those with diminutive hyperplastic polyps (p=0.0078). The maj...Continue Reading

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Citations

Jul 31, 2008·World Journal of Gastroenterology : WJG·Mitsuhiro Fujishiro
Feb 6, 2009·International Journal of Colorectal Disease·Sergio MoriniSalvatore M A Campo
Nov 23, 2006·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·C HassanS Morini
Jul 23, 2016·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Prasanna L PonugotiDouglas K Rex
Mar 1, 2011·International Immunopharmacology·Giuseppina MandalariSalvatore Cuzzocrea
Sep 21, 2010·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Ozgur GunebakmazIbrahim Ozdogru
May 9, 2007·Gastroenterology·Stephan R TarganUNKNOWN International Efficacy of Natalizumab in Crohn's Disease Response and Remission (ENCORE) Trial Group
Feb 3, 2009·Molecular Immunology·Natalia PetrakovaMaria Isaguliants
Jan 12, 2008·European Journal of Gastroenterology & Hepatology·Manabu KuromeYasushi Shiratori

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