Dioscorea nipponica Makino: a systematic review on its ethnobotany, phytochemical and pharmacological profiles

Chemistry Central Journal
Si-Hong Ou-YangTao Yi

Abstract

Dioscorea nipponica Makino is a perennial twining herbs belonging to the family Dioscoreaceae, which is mainly distributed in the northeastern, northern, eastern and central regions of China. Traditionally, the rhizome of this herb has been commonly used by Miao and Meng ethnic groups of China to treat rheumatoid arthritis, pain in the legs and lumbar area, Kashin Beck disease, bruises, sprains, chronic bronchitis, cough and asthma. Modern pharmacological studies have discovered that this herb possesses anti-tumor, anti-inflammatory, anti-diuretic, analgesic, anti-tussive, panting-calming and phlegm-dispelling activities, along with enhancing immune function and improving cardiovascular health. In recent years, both fat-soluble and water-soluble steroidal saponins were isolated from the rhizomes of D. nipponica using silica gel column chromatography, thin layer chromatography and high performance liquid chromatography methods. Saponin and sapogenins are mainly responsible for most of the pharmacological effects of this plant. Further, the chemical components of the aboveground parts contain more than 10 kinds of phenanthrene derivatives. The present review summarizes the knowledge concerning the geographical distribution, chemi...Continue Reading

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Citations

Sep 20, 2020·Foods·Jude E ObidiegwuCynthia A Chilaka
Nov 9, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Joo Tae HwangByoung Seob Ko
Dec 6, 2019·Journal of Ethnopharmacology·Dongdong WangVerena M Dirsch
May 1, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Gui-Ya YangLong Guo

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Methods Mentioned

BETA
MDA
flow
enzyme-linked immunosorbent assay
flow cytometry
bronchoalveolar
electron microscopy
organic solvent extraction

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