PMID: 8289765Jun 1, 1993Paper

Dipeptides in parenteral nutrition: from basic science to clinical applications

Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition
J A VazquezS A Adibi

Abstract

The use of intravenous dipeptides shows great promise as an avenue for the provision of amino acids that may otherwise be difficult to deliver via nutrient infusions. The physical/chemical properties and metabolism of numerous dipeptides have now been explored in experimental and human studies. It has been found that these agents have the capacity to spare nitrogen and support serum protein levels in a fashion equivalent to that of intravenous free amino acids. An additional benefit is the ability to deliver certain amino acids that are relatively unstable or poorly soluble in aqueous solutions. These various aspects of intravenous dipeptides are considered in this review.

References

Jul 1, 1978·The Journal of Nutrition·T T Daabees, L D Stegink
Dec 1, 1979·Metabolism: Clinical and Experimental·B A Krzysik, S A Adibi
Sep 1, 1976·Journal of Toxicology and Environmental Health·R H Mazur
Feb 1, 1992·Metabolism: Clinical and Experimental·J A VazquezS A Adibi
May 1, 1991·Cardiovascular and Interventional Radiology·S K StricklandJ J Raves
Jun 1, 1987·International Journal of Peptide and Protein Research·S Q LuoD J Graves
Dec 1, 1986·The American Journal of Physiology·T M ButlerS U Mooers
Aug 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·M F Boehm, J L Bada
Mar 1, 1984·Canadian Journal of Physiology and Pharmacology·H E Gallo-TorresC I Cheeseman

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Citations

Mar 27, 2012·Biotechnology and Bioengineering·Sohye KangRohini Deshpande
Jun 1, 1994·Burns : Journal of the International Society for Burn Injuries·M TenenhausW Nyhan
Jul 4, 2008·JPEN. Journal of Parenteral and Enteral Nutrition·Kenneth A Kudsk

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