Direct Allylic Amination of Allylic Alcohol Catalyzed by Palladium Complex Bearing Phosphine-Borane Ligand

Organic Letters
Goki HirataMasanari Kimura

Abstract

The direct electrophilic, nucleophilic, and amphiphilic allylations of allylic alcohol by use of a palladium catalyst and organometallic reagents such as organoborane and organozinc has been developed. The phosphine-borane compound works as the effective ligand for palladium-catalyzed direct allylic amination of allylic alcohol. Thus, with secondary amines, the reaction was completed in only 1 h, even at room temperature.

References

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Citations

Jun 15, 2018·Dalton Transactions : an International Journal of Inorganic Chemistry·Brian R NicholsBrian V Popp
Nov 30, 2018·Organic & Biomolecular Chemistry·Olatunji S OjoAlejandro Bugarin
Jan 22, 2019·Angewandte Chemie·Kazuishi FukudaJun Takaya
Apr 12, 2019·Dalton Transactions : an International Journal of Inorganic Chemistry·Fabio LorenziniBruce A Arndtsen

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