Direct Analysis of Free and Sulfite-Bound Carbonyl Compounds in Wine by Two-Dimensional Quantitative Proton and Carbon Nuclear Magnetic Resonance Spectroscopy

Analytical Chemistry
Maria NikolantonakiAndrew L Waterhouse

Abstract

Recent developments that have accelerated 2D NMR methods and improved quantitation have made these methods accessible analytical procedures, and the large signal dispersion allows for the analysis of complex samples. Few natural samples are as complex as wine, so the application to challenges in wine analysis look promising. The analysis of carbonyl compounds in wine, key oxidation products, is complicated by a multitude of kinetically reversible adducts, such as acetals and sulfonates, so that sample preparation steps can generate complex interferences. These challenges could be overcome if the compounds could be quantified in situ. Here, two-dimensional ((1)H-(1)H) homonuclear and heteronuclear ((13)C-(1)H) single quantum correlations (correlation spectroscopy, COSY, and heteronuclear single quantum coherence, HSQC) nuclear magnetic resonance spectra of undiluted wine samples were observed at natural abundance. These techniques achieve simultaneous direct identification and quantitation of acetaldehyde, pyruvic acid, acetoin, methylglyoxal, and α-ketoglutaric acid in wine with only a small addition of D2O. It was also possible to observe and sometimes quantify the sulfite, hydrate, and acetal forms of the carbonyl compounds. ...Continue Reading

References

Feb 1, 1973·Journal of the Science of Food and Agriculture·L F Burroughs, A H Sparks
Feb 1, 1973·Journal of the Science of Food and Agriculture·L F Burroughs, A H Sparks
Jan 1, 1980·Journal of Pharmaceutical Sciences·C LevayerJ Barbe
Aug 24, 2000·Journal of Agricultural and Food Chemistry·J C BarbeA Bertrand
Oct 24, 2001·The Journal of Organic Chemistry·Hugo E. GottliebAbraham Nudelman
Sep 15, 2005·Journal of Agricultural and Food Chemistry·Jessica DrinkineCédric Saucier
Feb 16, 2007·Journal of Agricultural and Food Chemistry·Jessica DrinkineCedric Saucier
Dec 18, 2007·Journal of Proteome Research·Que N VanTimothy D Veenstra
Jun 25, 2009·Analytical Chemistry·Wolfram GronwaldPeter J Oefner
Sep 25, 2009·Journal of Separation Science·Luciana C de AzevedoJailson B de Andrade

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Citations

Feb 10, 2017·Journal of the Science of Food and Agriculture·Guomin HanAndrew L Waterhouse
Oct 16, 2016·Journal of the Science of Food and Agriculture·Kostas IoannidisProkopios Magiatis
Jan 13, 2021·Foods·Marko ViskićAna Jeromel

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