Direct and crossed effects of somatosensory electrical stimulation on motor learning and neuronal plasticity in humans

European Journal of Applied Physiology
M P VeldmanTibor Hortobágyi

Abstract

Sensory input can modify voluntary motor function. We examined whether somatosensory electrical stimulation (SES) added to motor practice (MP) could augment motor learning, interlimb transfer, and whether physiological changes in neuronal excitability underlie these changes. Participants (18-30 years, n = 31) received MP, SES, MP + SES, or a control intervention. Visuomotor practice included 300 trials for 25 min with the right-dominant wrist and SES consisted of weak electrical stimulation of the radial and median nerves above the elbow. Single- and double-pulse transcranial magnetic stimulation (TMS) metrics were measured in the intervention and non-intervention extensor carpi radialis. There was 27 % motor learning and 9 % (both p < 0.001) interlimb transfer in all groups but SES added to MP did not augment learning and transfer. Corticospinal excitability increased after MP and SES when measured at rest but it increased after MP and decreased after SES when measured during contraction. No changes occurred in intracortical inhibition and facilitation. MP did not affect the TMS metrics in the transfer hand. In contrast, corticospinal excitability strongly increased after SES with MP + SES showing sharply opposite of these eff...Continue Reading

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Citations

Jan 31, 2016·Neuroscience Letters·Hannah Z LefumatFabrice R Sarlegna
Mar 26, 2016·Frontiers in Human Neuroscience·Menno P VeldmanTibor Hortobágyi
Aug 6, 2016·Neurobiology of Aging·Kelly M M BerghuisTibor Hortobágyi
May 25, 2016·PloS One·Fiorenzo MoscatelliGiuseppe Cibelli
Nov 15, 2017·Journal of Neuroengineering and Rehabilitation·Adelyn P Tu-ChanKarunesh Ganguly
Sep 10, 2019·The Journal of Physiology·Richard G Carson, Alison R Buick
May 7, 2019·Frontiers in Human Neuroscience·Ryuji OosawaKenichi Sugawara
May 25, 2021·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Claudia V TurcoAimee J Nelson
Jun 16, 2021·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·M P VeldmanT Hortobágyi
Oct 8, 2021·European Journal of Applied Physiology·Brodie J HandJohn G Semmler

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