Direct C-H cross-coupling approach to heteroaryl coumarins

Organic & Biomolecular Chemistry
Minsik MinSungwoo Hong

Abstract

A Pd-catalyzed direct cross-coupling of 3-bromocoumarins with heteroarenes provided an efficient route to synthesizing 3-heteroarylcoumarins. The reaction scope for the transformation was fairly broad, affording modest to good yields of various 3-heteroarylcoumarin scaffolds, which are privileged structures and prevalent motifs in many biologically active compounds and fluorophores.

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Citations

Feb 13, 2013·Beilstein Journal of Organic Chemistry·Maddi Sridhar ReddyMadala Haribabu
Aug 5, 2015·The Journal of Physical Chemistry. a·Irena DeperasińskaBoleslaw Kozankiewicz
Sep 23, 2014·Organic & Biomolecular Chemistry·Alexandre BruneauMouad Alami
Jul 8, 2015·Natural Product Reports·Fernanda G MedinaSoraya Osegueda-Robles
Jun 25, 2015·Chemical Communications : Chem Comm·Mehdi KhoobiAbbas Shafiee
Aug 9, 2018·Organic & Biomolecular Chemistry·Tao GuoYun-Hui Zhao
Apr 22, 2017·Frontiers in Microbiology·Duggirala SrideviMukesh Doble
Jun 27, 2014·Organic & Biomolecular Chemistry·Sanghye ShinSungwoo Hong

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