Direct costs of severe cutaneous adverse reactions in a tertiary hospital in Korea

The Korean Journal of Internal Medicine
Min-Suk YangHye-Ryun Kang

Abstract

There are only a few reports on the direct costs of severe cutaneous adverse reactions (SCARs), including drug reaction with eosinophilia and systemic symptoms (DRESS), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN), despite the tremendous negative impact these reactions can have on patients. We estimated the direct costs of treating SCARs. Patients admitted to a tertiary teaching hospital for the treatment of SCARs from January 1, 2005 to December 31, 2010 were included. Patients who had experienced SCARs during their admission for other medical conditions were excluded. The direct costs of hospitalization and outpatient department visits were collected. Inpatient and outpatient care costs were calculated, and factors affecting inpatient care costs were analyzed. The total healthcare cost for the management of 73 SCAR patients (36 with DRESS, 21 with SJS, and 16 with TEN) was 752,067 US dollars (USD). Most of the costs were spent on inpatient care (703,832 USD). The median inpatient care cost per person was 3,720 (range, 1,133 to 107,490) USD for DRESS, 4,457 (range, 1,224 to 21,428) USD for SJS, and 8,061 (range, 1,127 to 52,220) USD for TEN. Longer hospitalization significantly increased the inpatient c...Continue Reading

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Citations

Sep 27, 2019·Allergy·Cristobalina MayorgaMaría José Torres
Apr 24, 2019·Expert Review of Pharmacoeconomics & Outcomes Research·Min-Sun LeeEui-Kyung Lee
Sep 11, 2020·Journal of Cutaneous Medicine and Surgery·Jessica M S AsgarpourLoretta Fiorillo
Jun 8, 2019·Tropical Medicine & International Health : TM & IH·Lauren K KnightAnil Pooran
Oct 22, 2020·Pharmacoepidemiology and Drug Safety·Rema PanickarZoriah Aziz
Jan 5, 2021·Therapeutic Innovation & Regulatory Science·Sing Chet LeeVidhya Hariraj
Sep 23, 2020·The Journal of Allergy and Clinical Immunology. in Practice·Dong Yoon KangUNKNOWN Korean Severe Cutaneous Adverse Reactions Consortium
Jul 18, 2021·Clinics in Dermatology·Robert T SpauldingJeffrey P Callen

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