PMID: 8614072May 1, 1996Paper

Direct current reduces wound edema after full-thickness burn injury in rats

The Journal of Trauma
C S ChuB A Pruitt

Abstract

To observe the effect of 4 and 40 microA direct current (DC) on edema formation after burn injury in rats. Silver-nylon wound dressings were used as either anodes (-) or cathodes (+) on 20% total body surface area full-thickness scalds in anesthetized male Sprague-Dawley rats. Untreated burned rats and rats treated with silver-nylon dressings without current were used as controls. Immediately applied, continuous DC reduced burn edema by 17 to 48% at different times up to 48 hours postburn (p < 0.001). Neither reversal of electrode polarity nor change in current density had any significant effect on the results of treatment. Starting treatment during the first 8 hours postburn produced the least edema accumulation, but the reduction was significant even when DC was applied 36 hours afterburn. If started immediately after injury, treatment had to be continued a minimum of 8 hours to be most effective. Direct electric current has a beneficial effect in reducing wound edema after burn injury.

References

Jan 1, 1979·Scandinavian Journal of Plastic and Reconstructive Surgery·G Arturson, C E Jonsson
Nov 1, 1991·The Journal of Burn Care & Rehabilitation·T MatsudaH Reyes
Jul 11, 1991·The Journal of Burn Care & Rehabilitation·C S ChuB A Pruitt
Oct 1, 1989·Burns : Journal of the International Society for Burn Injuries·T KaufmanA Weinberg
Nov 1, 1968·The Journal of Trauma·H L Walker, A D Mason
Nov 1, 1981·The Journal of Trauma·D L de CamaraM C Robson
Jun 1, 1993·Burns : Journal of the International Society for Burn Injuries·I OnoM Matsuzaki
Jan 1, 1958·The Journal of Pathology and Bacteriology·S SEVITT

❮ Previous
Next ❯

Citations

Aug 1, 2007·Journal of Materials Science. Materials in Medicine·Lie MaChunmao Han
Jul 26, 2003·Burns : Journal of the International Society for Burn Injuries·Z F Tyack, J Ziviani
Aug 4, 1999·Burns : Journal of the International Society for Burn Injuries·T Gómez-CíaI Lopez
Jan 6, 2006·The Journal of Trauma·Shunichi SatoHiroshi Ashida
Aug 2, 2007·Journal of Burn Care & Research : Official Publication of the American Burn Association·Roger HuckfeldtPhillip J Finley
Nov 25, 2014·Burns : Journal of the International Society for Burn Injuries·David J BarilloMary Margaret-Brandt
Nov 25, 2014·Burns : Journal of the International Society for Burn Injuries·David E Marx, David J Barillo
Nov 25, 2014·Burns : Journal of the International Society for Burn Injuries·David J Barillo, David E Marx
Jan 4, 2012·Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists·June P Villeco
Nov 23, 2006·Burns : Journal of the International Society for Burn Injuries·T W ChiuA Burd
Mar 19, 2005·Burns : Journal of the International Society for Burn Injuries·Leopoldo C CancioCleon W Goodwin
Aug 19, 1999·The Journal of Trauma·C S ChuC W Goodwin
Feb 1, 2017·IEEE Transactions on Bio-medical Engineering·Neha BajwaZachary D Taylor
Mar 22, 2005·Muscle & Nerve·Haruki HigashimoriRichard C Carlsen
Aug 2, 2013·Annals of Plastic Surgery·Edward W MalinLeopoldo C Cancio
Oct 31, 2019·Journal of Burn Care & Research : Official Publication of the American Burn Association·Fatemeh SanjarKai P Leung
Oct 22, 2015·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Taiichiro IdaToshiaki Iwai

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.