Direct determination of the lamellar structure of peripheral nerve myelin at moderate resolution (7A)

Biophysical Journal
C R Worthington, T J McIntosh

Abstract

Low-angle X-ray diffraction patterns have been recorded from normal nerve and nerve swollen in glycerol solutions. The new X-ray data have a resolution of 7 A. Direct methods of structure analysis which include deconvolution of the auto-correlation function and sampling theorem reconstructions have been used in the interpretation of the X-ray data. Phases have been assigned to the first 12 orders of diffraction from normal nerve. Fourier syntheses at a resolution of 7 A are described and an absolute electron density scale is derived. A possible molecular interpretation of the electron density profile is given.

References

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Citations

Jun 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·W LesslauerJ K Blasie
Sep 26, 1973·Nature: New Biology·C R Worthington, T J McIntosh
Jun 20, 1972·Annals of the New York Academy of Sciences·C R Worthington
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Related Concepts

Rana pipiens
Glycerin
Structure of Sciatic Nerve
Electron Density
Plain X-ray
Myelin
Fourier Transform
X-Ray Diffraction
Perineurium
Radiographic Imaging Procedure

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