PMID: 8971654Nov 1, 1996Paper

Direct evidence of parasympathetic vasodilatation in cat periodontal ligament

Journal of Periodontal Research
T SasanoK Karita

Abstract

Sympathetic regulation of periodontal ligament blood flow (PLBF) is well-attested; however, vasodilator responses mediated by parasympathetic nerve fibers have yet to be conclusively demonstrated in the periodontal ligament (PL). The present study was designed to determine whether parasympathetic vasodilator mechanisms do or do not exist in the cat PL. In our cats, the cervical sympathetic trunks were sectioned bilaterally prior to any stimulation in order to eliminate sympathetic effects on the vascular beds under study. Dynamic changes in PLBF, with mandibular lip blood flow (LBF) recorded for comparison, were investigated in cat mandibular canine teeth using laser Doppler flowmetry. The peripheral cut ends of the facial and glossopharyngeal nerve roots, which have been reported to contain parasympathetic nerve fibers to the oral tissues, were electrically stimulated intracranially. Such stimulation caused blood flow to increase in the ipsilateral PL and lip, without an increase in systemic blood pressure. These vasodilator responses in the PL and lip were sensitive to ganglion blockade (with hexamethonium), indicating vasodilation via activation of parasympathetic vasodilator fibers. In contrast, although intracranial stimul...Continue Reading

References

Jul 1, 1979·Acta Physiologica Scandinavica·A BillG Nilsson
May 1, 1992·The Journal of Physiology·H Izumi, K Karita
Jul 1, 1992·Journal of the Autonomic Nervous System·K Karita, H Izumi
Jul 1, 1992·Journal of Periodontal Research·T SasanoK Karita
Dec 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·L J IgnarroG Chaudhuri
Jan 1, 1984·The Journal of Physiology·R Couture, A C Cuello
Oct 1, 1995·Journal of Dental Research·T SasanoK Karita
Jul 1, 1995·Journal of Periodontal Research·T SasanoD Sanjo
Jan 1, 1993·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·K NozakiS H Snyder
Jun 1, 1993·The Journal of Physiology·H Izumi, K Karita

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Citations

Sep 11, 2002·Archives of Oral Biology·Nobuyoshi ImamuraAkihiko Nakasima
Dec 26, 2001·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·G M Verdickt, P V Abbott
Mar 13, 2003·Journal of Clinical Periodontology·Antonios MavropoulosPål Brodin

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