Direct ionization methods in mass spectrometry: An overview

Analytica Chimica Acta
Christian W Klampfl, Markus Himmelsbach

Abstract

Within this paper a sub-group of ambient ionization mass spectrometry namely direct ionization mass spectrometry techniques are reviewed. They are characterized by the generation of an electrospray directly from the sample investigated. Prominent representatives include paper spray mass spectrometry, tissue spray mass spectrometry, probe electrospray ionization or thin-layer chromatography mass spectrometry. Applications of all major direct ionization techniques within different fields such as biomedical analysis, analysis of natural products, analysis of technical products and food analysis, just to name a few, are discussed and relevant parameters are listed in five Tables.

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Citations

Feb 19, 2016·Analytical Chemistry·Erin GemperlineLingjun Li
Feb 7, 2016·Analytica Chimica Acta·Luis Cuadros-RodríguezAntonio González-Casado
Oct 1, 2015·Analytical Chemistry·Dalton T SnyderR Graham Cooks
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Jan 21, 2017·Analytical Chemistry·Patricia M PeacockSarah Trimpin
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