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Direct microinjection of soman or VX into the amygdala produces repetitive limbic convulsions and neuropathology

Brain Research

Dec 1, 1987

John H McDonoughM T Nipwoda

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Abstract

Rats were injected in the amygdala and other forebrain sites with nmolar amounts of the highly toxic organophosphate 'nerve agent' compounds soman or VX (O-ethyl-S-(2-diisopropylaminoethyl)-methylphosphonothioate) in an attempt to determine the mechanism(s) responsible for the permanent...read more

Mentioned in this Paper

Microinjections
Brain Damage, Chronic
Anoxia
Metazoa
Brain
Methylphosphonothioic acid S-(2-(bis(1-methylethyl)amino)ethyl) O-ethyl ester
Amygdaloid Structure
Soman
August Rats
Organothiophosphorus Compounds
Paper Details
References
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  • Citations54
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Direct microinjection of soman or VX into the amygdala produces repetitive limbic convulsions and neuropathology

Brain Research

Dec 1, 1987

John H McDonoughM T Nipwoda

PMID: 3427447

DOI: 10.1016/0006-8993(87)91593-9

Abstract

Rats were injected in the amygdala and other forebrain sites with nmolar amounts of the highly toxic organophosphate 'nerve agent' compounds soman or VX (O-ethyl-S-(2-diisopropylaminoethyl)-methylphosphonothioate) in an attempt to determine the mechanism(s) responsible for the permanent...read more

Mentioned in this Paper

Microinjections
Brain Damage, Chronic
Anoxia
Metazoa
Brain

Related Papers

Paper Details
References
  • References40
  • Citations54
1234
  • References40
  • Citations54
12345...

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