Direct pixel to pixel principal strain mapping from tagging MRI using end to end deep convolutional neural network (DeepStrain).

Scientific Reports
Khaled Z Abd-ElmoniemAhmed M Gharib

Abstract

Regional soft tissue mechanical strain offers crucial insights into tissue's mechanical function and vital indicators for different related disorders. Tagging magnetic resonance imaging (tMRI) has been the standard method for assessing the mechanical characteristics of organs such as the heart, the liver, and the brain. However, constructing accurate artifact-free pixelwise strain maps at the native resolution of the tagged images has for decades been a challenging unsolved task. In this work, we developed an end-to-end deep-learning framework for pixel-to-pixel mapping of the two-dimensional Eulerian principal strains [Formula: see text] and [Formula: see text] directly from 1-1 spatial modulation of magnetization (SPAMM) tMRI at native image resolution using convolutional neural network (CNN). Four different deep learning conditional generative adversarial network (cGAN) approaches were examined. Validations were performed using Monte Carlo computational model simulations, and in-vivo datasets, and compared to the harmonic phase (HARP) method, a conventional and validated method for tMRI analysis, with six different filter settings. Principal strain maps of Monte Carlo tMRI simulations with various anatomical, functional, and...Continue Reading

References

Aug 1, 1990·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·T J Mosher, M B Smith
Jun 1, 1989·Radiology·L Axel, L Dougherty
Aug 1, 1993·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S E FischerP Boesiger
Nov 26, 1999·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·N F OsmanJ L Prince
May 31, 2008·Medical Image Analysis·Khaled Z Abd-ElmoniemJerry L Prince
Jul 29, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Harsh K AgarwalKhaled Z Abd-Elmoniem
Feb 22, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Sohae ChungLeon Axel
Jul 30, 2011·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·El-Sayed H Ibrahim
Oct 15, 2011·IEEE Transactions on Medical Imaging·Hui Wang, Amir A Amini
Jun 3, 2017·IEEE Transactions on Medical Imaging·Jelmer M WolterinkIvana Isgum
Mar 29, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Weiyi ChenKrishna S Nayak
Sep 16, 2019·Medical Image Analysis·Xin YiPaul Babyn
Dec 8, 2019·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Karim ArmaniousBin Yang

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