Direct quantitative measurement of the C═O⋅⋅⋅H-C bond by atomic force microscopy

Science Advances
Shigeki KawaiAdam S Foster

Abstract

The hydrogen atom-the smallest and most abundant atom-is of utmost importance in physics and chemistry. Although many analysis methods have been applied to its study, direct observation of hydrogen atoms in a single molecule remains largely unexplored. We use atomic force microscopy (AFM) to resolve the outermost hydrogen atoms of propellane molecules via very weak C═O⋅⋅⋅H-C hydrogen bonding just before the onset of Pauli repulsion. The direct measurement of the interaction with a hydrogen atom paves the way for the identification of three-dimensional molecules such as DNAs and polymers, building the capabilities of AFM toward quantitative probing of local chemical reactivity.

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Citations

Feb 28, 2018·Angewandte Chemie·Leo GrossGerhard Meyer
Mar 24, 2018·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Arpita VaradwajKoichi Yamashita
Apr 18, 2018·Science Advances·Shigeki KawaiAdam S Foster
Dec 21, 2019·Physical Chemistry Chemical Physics : PCCP·Jakub DąbrowskiArkadiusz Ptak
Jul 3, 2018·Science Advances·Joonhee LeeV Ara Apkarian
May 30, 2020·Physical Review Letters·Alfred J WeymouthFranz J Giessibl
Apr 27, 2019·International Journal of Molecular Sciences·Hong ZhangPing Yu
Jul 20, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ruijing WangQingzhong Li
Feb 3, 2019·The Review of Scientific Instruments·Franz J Giessibl
Oct 9, 2020·Beilstein Journal of Nanotechnology·Linda LaflörPhilipp Rahe
Jul 11, 2021·The Review of Scientific Instruments·Omur E Dagdeviren
Jul 20, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Franz J Giessibl
Jun 25, 2020·ACS Applied Materials & Interfaces·Shi Xuan LeongXing Yi Ling
Jun 9, 2020·The Journal of Physical Chemistry Letters·Qingyang DuPing Yu
Aug 14, 2020·The Journal of Physical Chemistry Letters·Yuuki AdachiYan Jun Li
Sep 26, 2021·Nature Communications·Pengcheng ChenNan Yao

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Methods Mentioned

BETA
nuclear
x-ray crystallography
transmission electron microscopy
scanning tunneling microscopy
atomic force microscopy
AFM

Software Mentioned

CHARMM
VASP ( Vienna ab initio simulation package )

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