PMID: 11920531Mar 29, 2002Paper

Direct visual inspection for cervical cancer screening: an analysis of factors influencing test performance

Cancer
Lynette DennyThomas C Wright

Abstract

The authors evaluated direct visual inspection of the cervix after the application of 5% acetic acid (DVI) as a cervical cancer screening test for use in low-resource settings. Four tests were used to screen 2754 previously unscreened women: DVI with and without x4.5 magnification and differentiating between all lesions and well-circumscribed lesions; testing for high-risk types of human papillomavirus DNA using the Hybrid Capture II assay, cervical cytology, and Cervicography. Women with positive results on any of the four screening tests were referred for colposcopy and histologic sampling. All women were tested for N. gonorrhea, C. trachomatis, T. vaginalis, and human immunodeficiency virus 1. Histologically confirmed carcinoma was diagnosed in 21 women (0.8%), high-grade squamous intraepithelial lesions (SILs) were diagnosed in 96 women (3.5%), and low-grade SILs were diagnosed in 102 women (3.7%). The estimated sensitivity of DVI when performed without magnification for high-grade SILs was 70%, with an estimated specificity of 79%. Magnification did not significantly improve sensitivity for high-grade SILs (74% with magnification) but significantly reduced specificity (77%). Restricting the definition of a positive DVI tes...Continue Reading

References

Jul 15, 1984·International Journal of Cancer. Journal International Du Cancer·N AristizabalW Haenszel
Apr 1, 1995·American Journal of Epidemiology·M T FaheyP Macaskill
Jan 1, 1994·Diagnostic Cytopathology·E C Lazcano-PonceM Hernandez-Avila
May 1, 1996·Acta Cytologica·E C Lazcano-PonceH E Velasco-Mondragón
Sep 1, 1996·Obstetrics and Gynecology·E MegevandB Bloch
Feb 6, 1999·International Journal of Cancer. Journal International Du Cancer·R SankaranarayananM K Nair
Aug 15, 2000·American Journal of Obstetrics and Gynecology·L DennyT C Wright
Jun 28, 2001·JAMA : the Journal of the American Medical Association·S J GoldieT C Wright

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Citations

Mar 11, 2003·Transactions of the Royal Society of Tropical Medicine and Hygiene·R Sankaranarayanan
Apr 5, 2003·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·J L WinklerJ W Sellors
Jun 17, 2003·Journal of the National Cancer Institute. Monographs·Thomas C Wright
Jul 19, 2003·Tropical Medicine & International Health : TM & IH·P ClaeysM Temmerman
Dec 17, 2003·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·A SingerA Deery
Mar 22, 2006·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·E-S Abdel-HadyM Abo-Elkheir
Jun 29, 2006·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·A Longatto-FilhoK Syrjänen
Dec 16, 2006·Cytopathology : Official Journal of the British Society for Clinical Cytology·P SodhaniA Sehgal
Jul 4, 2008·Journal of Lower Genital Tract Disease·Amr H El-ShalakanyZeinab Sehab El Din
Nov 26, 2008·Reproductive Health Matters·Lynette Denny
Jan 15, 2009·Nature Reviews. Cancer·Nadhi Thekkek, Rebecca Richards-Kortum
Oct 7, 2014·International Journal of Cancer. Journal International Du Cancer·Pierre-Marie TebeuPatrick Petignat
Mar 1, 2018·Climacteric : the Journal of the International Menopause Society·P J TolimanA J Vallely
Feb 12, 2004·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·H S Cronjé
Oct 13, 2005·Statistics in Medicine·Kam-Fai WongLouise Kuhn
Apr 13, 2005·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·J BradleyS Luciani
Nov 18, 2005·Cost Effectiveness and Resource Allocation : C/E·Jeremy D Goldhaber-FiebertSue J Goldie
Sep 24, 2009·Tropical Medicine & International Health : TM & IH·Karly S LouiePhilippe Mayaud
Oct 14, 2009·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·I LataifehY Khader
Jul 8, 2010·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Pakhee AggarwalVijay Zutshi
Jan 23, 2013·Clinical Obstetrics and Gynecology·Leslie Bradford, Annekathryn Goodman
Oct 5, 2010·Journal of the National Cancer Institute·Lynette DennyThomas C Wright
Dec 25, 2004·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·A GoelP Sachdeva
Apr 13, 2005·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·V D Tsu, A E Pollack
Aug 17, 2005·BJOG : an International Journal of Obstetrics and Gynaecology·Lynette Denny
Dec 17, 2003·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·P S BasuUNKNOWN Calcutta Cervical Cancer Early Detection Group
Mar 5, 2008·Journal of Biomedical Optics·Sun Young ParkRebecca Richards-Kortum
Oct 3, 2006·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·P F EscobarJ L Belinson
Apr 19, 2006·International Journal of Cancer. Journal International Du Cancer·Ghislain Sangwa-LugomaEduardo L Franco
Oct 27, 2006·International Journal of Cancer. Journal International Du Cancer·Qi ZhangThomas C Wright
Apr 18, 2007·International Journal of Cancer. Journal International Du Cancer·Maribel AlmontePeter Sasieni
Feb 7, 2015·Biomedical Optics Express·Kuan PengJiaying Xiao
Jun 1, 2013·Archives of Pathology & Laboratory Medicine·Rosemary Tambouret
Feb 13, 2004·International Journal of Cancer. Journal International Du Cancer·Rengaswamy SankaranarayananJacob Cherian
Apr 13, 2005·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·R SankaranarayananS Robles
Sep 25, 2004·Cancer·Eric J Suba, Stephen S Raab
Jan 29, 2011·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Miriam CremerJuan Felix
Jan 8, 2009·British Journal of Cancer·N LiG Clifford

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