PMID: 573466Jul 1, 1979

Direct visualization of cell to cell coupling: transfer of fluorescent probes in living mammalian pancreatic acini

Pflügers Archiv : European journal of physiology
N Iwatsuki, O H Petersen


A technique whereby it is possible directly to observe the movement of organic molecules from cell to cell in living mammalian exocrine glands is described. Thin translucent segments of mouse pancreas are mounted in a superfusion bath. Fluorescent probes are injected intracellularly via fine micropipettes and fluorescence observed. Both fluorescein (mol. wt. 332) and procion yellow (mol. wt. 697) are shown to be transferred from the injection cell to neighbouring acinar cells. This shows directly the existence of intercellular communicating pathways.


May 1, 1978·Biological Reviews of the Cambridge Philosophical Society·R M Case
Oct 15, 1979·Experientia·J R Martinez, O H Petersen
Apr 28, 1978·Annals of the New York Academy of Sciences·W R LOEWENSTEIN, B Rose
Apr 28, 1978·Annals of the New York Academy of Sciences·O H Peterson, N Iwatsuki
Sep 6, 1978·Pflügers Archiv : European journal of physiology·M L RobertsO H Petersen
Nov 1, 1978·The Journal of Cell Biology·N Iwatsuki, O H Petersen
Jan 1, 1978·The Journal of Physiology·N Iwatsuki, O H Petersen
Feb 1, 1978·The Journal of Physiology·M G Hammer, J D Sheridan
Oct 1, 1978·The Journal of Cell Biology·S B Kater, N J Galvin
Nov 1, 1978·The Journal of Physiology·J Graf, O H Petersen
Jun 3, 1977·The Journal of Membrane Biology·S J Socolar
Jul 14, 1966·Annals of the New York Academy of Sciences·W R LOEWENSTEIN
Jul 14, 1966·Annals of the New York Academy of Sciences·M V Bennett
Sep 1, 1964·The Journal of Cell Biology·W R LOEWENSTEIN, Y KANNO


Jul 1, 1980·Pflügers Archiv : European journal of physiology·R Laugier, O H Petersen
Jul 1, 1980·Pflügers Archiv : European journal of physiology·N Iwatsuki, O H Petersen
Mar 1, 1988·Developmental Biology·E WinterhagerH W Denker
Dec 1, 1996·Clinical and Experimental Pharmacology & Physiology·P Meda
Oct 1, 1988·European Journal of Clinical Investigation·R Bruzzone, P Meda
Aug 1, 1996·Journal of Bioenergetics and Biomembranes·P Meda
Jun 28, 2002·Physiological Reviews·Michael C Ashby, Alexei V Tepikin
Feb 10, 2012·Pancreas·Mihnea I Nicolescu, Laurentiu M Popescu
Oct 1, 1981·Scottish Medical Journal·S T Green
Apr 7, 2017·Pflügers Archiv : European journal of physiology·Pawel E Ferdek, Monika A Jakubowska

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