Directed evolution of the optoelectronic properties of synthetic nanomaterials

Chemical Communications : Chem Comm
Benjamin LambertArdemis A Boghossian

Abstract

Directed evolution is a powerful approach to tailor protein properties toward new or enhanced functions. Herein, we use directed evolution to engineer the optoelectronic properties of DNA-wrapped single-walled carbon nanotube sensors through DNA mutation. This approach leads to an improvement in the fluorescence intensity of 56% following two evolution cycles.

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Citations

Oct 17, 2019·Frontiers in Chemistry·Alice J Gillen, Ardemis A Boghossian
Jun 24, 2021·Nature Communications·Sang-Hyun OhMichael S Strano
May 23, 2020·The Journal of Physical Chemistry Letters·Benjamin Paul LambertArdemis Anoush Boghossian

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Methods Mentioned

BETA
biosensing
Fluorescence

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