Directional blood flow imaging in volumetric optical microangiography achieved by digital frequency modulation.

Optics Letters
Ruikang K Wang

Abstract

An effective digital frequency modulation approach to achieve directional blood flow imaging within microcirculations in tissue beds in vivo for optical microangiography is presented. The method only requires the system to capture one three-dimensional data set within which the interferograms are modulated by a constant frequency modulation that gives one directional flow information. The result is that the imaging speed is doubled and the computational load is halved. The method is experimentally validated by a flow phantom and is tested for imaging of cerebral vascular blood perfusion in a live mouse with the cranium left intact.

Citations

Aug 31, 2011·Hearing Research·Xiaorui Shi
Oct 12, 2010·Journal of Neuroscience Methods·Yali Jia, Ruikang K Wang
Jun 20, 2012·Journal of Biophotonics·Susan M Daly, Martin J Leahy
Jul 12, 2011·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Stephen P Morgan
Jul 27, 2010·IEEE Journal of Selected Topics in Quantum Electronics : a Publication of the IEEE Lasers and Electro-optics Society·Ruikang K Wang
Mar 9, 2017·Biomedical Optics Express·Chieh-Li Chen, Ruikang K Wang
Jan 22, 2015·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·C MagnainM Atlan
Oct 17, 2015·Journal of Biomedical Optics·Anqi ZhangRuikang K Wang

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