Disability of Dialysis Patients and the Condition of Blood Vessels

Journal of Clinical Medicine
Tomasz GołębiowskiMagdalena Krajewska

Abstract

The number of elderly hemodialysis patients is constantly increasing worldwide. This population has a high burden of comorbid conditions, which impair daily activities. The aim of the study was to analyze problems of disability in hemodialysis patients in the context of cardiovascular (CV) complications and vascular condition. In this cross-sectional study, 129 patients (mean age 64.5) were enrolled. The degree of disability in Barthel index (Bi) and 10-year cardiovascular risk (QRISK®3) were assessed. A Mobil-O-Graph monitor was used for measuring hemodynamic parameters. Only 6.2% of patients were professionally active, 19% used a wheelchair for transport, and 16% used crutches. More than half (51%) were independent in everyday activities reaching 80-100 points on Bi. The rest, with Bi < 80, were considered as dependent. The most common causes of disability were CV complications. The independent group (80-100 points) was characterized by significantly lower pulse wave velocity (PWV) and lower QRISK®3 compared to dependent patients. The degree of disability negatively correlated with age, PWV, and QRISK®3. Multivariate logistic regression revealed that disability (Bi < 80) was independently associated with CV events in the past...Continue Reading

References

Jan 1, 1988·International Disability Studies·D T Wade, C Collin
Aug 1, 1993·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·G E MooreJ H Mitchell
Mar 17, 2001·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·L P FriedUNKNOWN Cardiovascular Health Study Collaborative Research Group
Jan 29, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Ann M O'HareKirsten L Johansen
Mar 18, 2005·Seminars in Dialysis·Diane WuerthFredric O Finkelstein
Apr 5, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Austin G StackBhamidipati V R Murthy
Mar 21, 2008·Kidney International·W L Cook, S V Jassal
Oct 16, 2009·The New England Journal of Medicine·Manjula Kurella TamuraCharles E McCulloch
Nov 21, 2009·Journal of Hypertension·Mohamed TemmarZiad Massy
Dec 25, 2009·Journal of Atherosclerosis and Thrombosis·Robert G FassettJeff S Coombes
May 26, 2011·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Hartmut H MallucheMarie-Claude Monier-Faugere
Mar 2, 2012·Kidney & Blood Pressure Research·Tomasz GołębiowskiMarian Klinger
Oct 13, 2012·Journal of the American Geriatrics Society·Mara A McAdams-DemarcoDorry L Segev
Oct 26, 2012·Seminars in Dialysis·Janine Farragher, Sarbjit Vanita Jassal
Jul 31, 2014·Clinical Journal of the American Society of Nephrology : CJASN·Naohito IsoyamaJuan Jesús Carrero
Oct 12, 2014·American Journal of Hypertension·James E SharmanJeff S Coombes
Oct 23, 2014·Clinical Interventions in Aging·Natalia Aquaroni RicciMonica Rodrigues Perracini
Mar 4, 2015·Hemodialysis International·Niall T KavanaghManjula Kurella Tamura
Mar 4, 2015·Journal of the American Society of Nephrology : JASN·Stephanie ThompsonUNKNOWN Alberta Kidney Disease Network
Nov 28, 2015·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·S Vanita JassalFrancesca Tentori
May 4, 2016·International Journal of Cardiology·Stefan D AnkerUNKNOWN On behalf the ARO Steering Committee (collaborators)
Sep 13, 2017·Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation·Ryota MatsuzawaAtsuhiko Matsunaga
Mar 25, 2018·Journal of Nephrology·Maurizio BossolaUNKNOWN Dialysis and Transplant Lazio Region Registry Scientific Committee
May 2, 2018·Hypertension·Giovanni TripepiGerard London
Aug 31, 2018·European Heart Journal·Bryan WilliamsUNKNOWN ESC Scientific Document Group
Nov 2, 2018·Nephron·Namiko A GotoMarije E Hamaker
Nov 6, 2018·PloS One·Malgorzata DebowskaJacek Waniewski
Dec 6, 2018·International Urology and Nephrology·Irina Mihaela AbdulanAdrian Covic
Mar 28, 2019·American Journal of Nephrology·Julia MatschkalChristoph Schmaderer

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Methods Mentioned

BETA
amputation

Software Mentioned

Statistica
QRISK

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