Disabling chronic conditions in childhood and socioeconomic disadvantage: a systematic review and meta-analyses of observational studies

BMJ Open
Nicholas J SpencerJanet M Read

Abstract

To determine the association of socioeconomic disadvantage with the prevalence of childhood disabling chronic conditions in high-income countries. Systematic review and meta-analyses. 6 electronic databases, relevant websites, reference lists and experts in the field. 160 observational studies conducted in high-income countries with data on socioeconomic status and disabling chronic conditions in childhood, published between 1 January 1991 and 31 December 2013. Abstracts were reviewed, full papers obtained, and papers identified for inclusion by 2 independent reviewers. Inclusion decisions were checked by a third reviewer. Where reported, ORs were extracted for low versus high socioeconomic status. For studies reporting raw data but not ORs, ORs were calculated. Narrative analysis was undertaken for studies without data suitable for meta-analysis. 126 studies had data suitable for meta-analysis. ORs for risk estimates were: all-cause disabling chronic conditions 1.72 (95% CI 1.48 to 2.01); psychological disorders 1.88 (95% CI 1.68 to 2.10); intellectual disability 2.41 (95% CI 2.03 to 2.86); activity-limiting asthma 2.20 (95% CI 1.87 to 2.85); cerebral palsy 1.42 (95% CI 1.26 to 1.61); congenital abnormalities 1.41 (95% CI 1.24...Continue Reading

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Citations

Oct 30, 2016·The Journal of Pediatrics·So Hyun KimUNKNOWN Extremely Low Gestational Age Newborn (ELGAN) Study Investigators
Jun 15, 2017·Dermatitis : Contact, Atopic, Occupational, Drug·Alexandra R VaughnVivian Y Shi
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Sep 22, 2017·American Journal of Public Health·Maureen S DurkinMarshalyn Yeargin-Allsopp
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Oct 7, 2020·European Journal of Public Health·Asri MaharaniUNKNOWN SENSE-Cog WP1 group
Oct 31, 2020·Child: Care, Health and Development·Eric Emerson, Gwynnyth Llewellyn
Jan 21, 2021·Clinical Journal of the American Society of Nephrology : CJASN·Lucy A PlumbYoav Ben-Shlomo
Nov 23, 2021·Child: Care, Health and Development·Anita van ZwietenGermaine Wong

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