PMID: 1202586Nov 26, 1975Paper

Disaccharidases in rat small intestinal mucosa following cytostatic treatment with adriamycin

Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie
G HartwichH J Pesch

Abstract

Our studies have shown that appropriate doses of adriamycin can reduce the activities of the intestinal disaccharidases in the rat. At higher doses, in addition to morphological changes in the intestinal mucosa, a considerable fall in disaccharidase activities also occurs. This functional impairment can be seen for a period of several days after the morphological restitution of the mucosa. Appropriate studies of the small intestinal mucosa in man will have to be undertaken to show whether similar impairment occurs at therapeutic doses.

References

Oct 1, 1974·Klinische Wochenschrift·G HartwichH Prestele
Feb 1, 1973·Acta Radiologica: Therapy, Physics, Biology·J Stone, P J Cheshire
Feb 1, 1969·The American Journal of Clinical Nutrition·T M Bayless, N L Christopher
Mar 1, 1971·Biochimica Et Biophysica Acta·R J GrandK J Isselbacher
Jan 1, 1967·Pflügers Archiv für die gesamte Physiologie des Menschen und der Tiere·J D Schlenker, J W Robinson
Mar 1, 1970·The Journal of Clinical Investigation·J J HerbstN Kretchmer
Jan 1, 1970·The American Journal of the Medical Sciences·T F RaceW W Faloon
Mar 1, 1970·The American Journal of Digestive Diseases·M I Cohen, H McNamara
Nov 1, 1970·Acta paediatrica Scandinavica·A DahlqvistM Akerman
Jan 1, 1968·Analytical Biochemistry·A Dahlqvist
May 1, 1969·The American Journal of Digestive Diseases·J L Achord
Jan 1, 1964·Analytical Biochemistry·A DAHLQVIST
Jan 1, 1963·Enzymologia Biologica Et Clinica·S AURICCHIOA PRADER
Nov 12, 1964·The New England Journal of Medicine·G R PLOTKIN, K J ISSELBACHER

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Citations

Sep 1, 1994·Cancer·H L ParnesC A Schiffer
Feb 15, 1982·Cancer·J S HyamsS E Sallan
Jan 1, 1984·Acta neurochirurgica·H InoueC Ohye
Jun 15, 1978·Klinische Wochenschrift·R Ecknauer, K Rommel
Apr 1, 1988·Baillière's Clinical Gastroenterology·B Lembcke, W F Caspary

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