Discharge educational strategies for reduction of vascular events (DESERVE): design and methods

International Journal of Stroke : Official Journal of the International Stroke Society
Aaron S LordBernadette Boden-Albala

Abstract

Stroke and vascular risk factors disproportionately affect minority populations, with Blacks and Hispanics experiencing a 2·5- and 2·0-fold greater risk compared with whites, respectively. Patients with transient ischemic attacks and mild, nondisabling strokes tend to have short hospital stays, rapid discharges, and inaccurate perceptions of vascular risk. The primary aim of the Discharge Educational Strategies for Reduction of Vascular Events (DESERVE) trial is to evaluate the efficacy of a novel community health worker-based multilevel discharge intervention vs. standard discharge care on vascular risk reduction among racially/ethnically diverse transient ischemic attack/mild stroke patients at one-year postdischarge. We hypothesize that those randomized to the discharge intervention will have reduced modifiable vascular risk factors as determined by systolic blood pressure compared with those receiving usual care. Given 300 subjects per group and alpha of 0·05, the power to detect a 6 mmHg reduction in systolic blood pressure is 89%. DESERVE trial is a prospective, randomized, multicenter clinical trial of a novel discharge behavioral intervention. Patients with transient ischemic attack/mild stroke are randomized during hos...Continue Reading

References

Aug 4, 2001·Stroke; a Journal of Cerebral Circulation·R L SaccoS Shea
Oct 22, 2002·Prevention Science : the Official Journal of the Society for Prevention Research·Karol L KumpferNikki Bellamy
Oct 28, 2003·Disease Management : DM·Thomas Bodenheimer
Feb 6, 2004·Stroke; a Journal of Cerebral Circulation·Brett KisselaJoseph Broderick
Jun 6, 2009·Stroke; a Journal of Cerebral Circulation·Dawn KleindorferBrett M Kissela
Mar 3, 2010·Contemporary Clinical Trials·Bernadette Boden-AlbalaMyunghee C Paik
Jun 5, 2013·Stroke; a Journal of Cerebral Circulation·Bernadette Boden-Albala, Leigh W Quarles

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Citations

May 8, 2018·The Cochrane Database of Systematic Reviews·Bernadeta BridgwoodPriya Modi
Dec 10, 2020·Implementation Science Communications·Temitope OjoBernadette Boden-Albala
Nov 24, 2021·The Cochrane Database of Systematic Reviews·Thomas F CrockerAnne Forster

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Clinical Trials Mentioned

NCT01836354

Software Mentioned

TTM
DESERVE

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