Discharge of vagal pulmonary receptors differentially alters neural activities during various stages of expiration in the cat

The Journal of Physiology
W M St John, D Zhou

Abstract

1. The purpose was to evaluate the hypothesis that neural expiration is composed of two phases: I, a post inspiratory period; and II, the period at which expiratory activities of spinal nerves reach peak values. We hypothesized that the discharge of pulmonary stretch receptors might differentially alter neural activities during these two phases. 2. Activities of the phrenic nerve, intercostal nerve and nerves innervating the thyroarytenoid muscle of the larynx and triangularis sterni muscle of the chest wall were recorded in decerebrate and paralysed cats. 3. The experimental animals were ventilated with a servo-respirator which produced changes in tracheal pressure, and lung volume, in parallel with alterations in integrated activity of the phrenic nerve. 4. In order to assess the influence of the discharge of slowly adapting pulmonary stretch receptors upon neural activities during expiration, lung volume was held at end-expiratory or end-inspiratory levels for individual respiratory cycles. 5. When pulmonary inflation was prevented, phrenic activity increased, as did activity of the thyroarytenoid nerve during early expiration. In contrast, activities of the triangularis sterni and intercostal nerves during mid- to late expi...Continue Reading

Citations

Sep 1, 1991·Respiration Physiology·E van Lunteren
Nov 1, 1990·Respiration Physiology·R F FregosiW M St John
Dec 18, 2001·Journal of Applied Physiology·Stephen RyanPhilip Nolan
Mar 15, 2002·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Mathias Dutschmann, Julian F R Paton
Jun 10, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·X Zhang, E N Bruce
Sep 1, 1995·Respiration Physiology·F WalloisB Duron

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