Discontinuing Treatment Against Medical Advice: The Role of Perceived Autonomy Support From Providers in Relapsing-Remitting Multiple Sclerosis

Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine
Morgan GlusmanJared Bruce

Abstract

Long-term medication adherence is problematic among patients with chronic medical conditions. To our knowledge, this was the first study to examine factors associated with nonadherence among patients with relapsing-remitting multiple sclerosis who discontinue disease-modifying treatments against medical advice. To examine differences in perceived provider autonomy support between disease-modifying treatment-adherent relapsing-remitting multiple sclerosis patients and relapsing-remitting multiple sclerosis patients who discontinued disease-modifying treatments against medical advice. Self-report questionnaires and a neurologic exam were administered to demographically matched adherent (n = 50) and nonadherent (n = 79) relapsing- remitting multiple sclerosis patients from the Midwest and Northeast USA. Adherent patients reported greater perceived autonomy support from their treatment providers, F(1, 124) = 28.170, p < .001, partial η2 = .185. This difference persisted after controlling for current multiple sclerosis healthcare provider, education, disease duration, Expanded Disability Status Scale, perceived barriers to adherence, and prevalence of side effects, F(1, 121) = 9.61, p = .002, partial η2 = .074. Neither depressive sy...Continue Reading

References

Oct 1, 1992·Journal of Behavioral Medicine·C D SherbourneR L Kravitz
Dec 31, 1997·Annals of Internal Medicine·M Von KorffE H Wagner
Jun 10, 1998·Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association·G C WilliamsE L Deci
Jul 2, 2003·The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses·Cira FraserTimothy Vollmer
May 24, 2005·Medical Care·Michael C SokolRobert S Epstein
Nov 12, 2005·Annals of Neurology·Chris H PolmanJerry S Wolinsky
Feb 27, 2007·Journal of Pediatric Health Care : Official Publication of National Association of Pediatric Nurse Associates & Practitioners·Bonnie Gance-Cleveland
May 16, 2009·Journal of Neurology·Katherine TreadawayElliot M Frohman
Dec 10, 2009·Multiple Sclerosis : Clinical and Laboratory Research·Jared M BruceSharon G Lynch
Jun 22, 2010·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·V DevonshireUNKNOWN GAP Study Group
Nov 6, 2010·The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses·Christina CaonJennifer Shoemaker
Nov 6, 2010·The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses·Carol SaundersJennifer Shoemaker
Dec 24, 2010·Therapeutic Advances in Neurological Disorders·Ralf GoldGiancarlo Comi
Apr 26, 2011·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Janice WongPaul W O'Connor
Jul 6, 2011·Nature Reviews. Neurology·Jared M Bruce, Sharon G Lynch
Jan 4, 2013·The New England Journal of Medicine·Emily Oshima Lee, Ezekiel J Emanuel
Apr 13, 2013·Clinical Medicine & Research·Sharon J RolnickRichard J Bruzek
May 29, 2013·Journal of the Neurological Sciences·C HeesenJ Kasper
Jan 24, 2014·International Journal of MS Care·Gina RemingtonKatherine Treadaway
Apr 24, 2014·Multiple Sclerosis : Clinical and Laboratory Research·Christoph HeesenPaul Bissell
Jul 1, 2012·Perspectives on Psychological Science : a Journal of the Association for Psychological Science·Johan Y Y NgGeoffrey C Williams
Nov 14, 2015·Journal of Behavioral Medicine·Jared BruceDelwyn Catley
Dec 17, 2015·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Jared M BruceDavid P Jarmolowicz

❮ Previous
Next ❯

Citations

Nov 11, 2018·Neurology and Therapy·David YeandleDawn Langdon

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.