Discovery and validation of genomic regions associated with resistance to maize lethal necrosis in four biparental populations

Molecular Breeding : New Strategies in Plant Improvement
Manje GowdaB M Prasanna

Abstract

In sub-Saharan Africa, maize is the key determinant of food security for smallholder farmers. The sudden outbreak of maize lethal necrosis (MLN) disease is seriously threatening the maize production in the region. Understanding the genetic basis of MLN resistance is crucial. In this study, we used four biparental populations applied linkage mapping and joint linkage mapping approaches to identify and validate the MLN resistance-associated genomic regions. All populations were genotyped with low to high density markers and phenotyped in multiple environments against MLN under artificial inoculation. Phenotypic variation for MLN resistance was significant and heritability was moderate to high in all four populations for both early and late stages of disease infection. Linkage mapping revealed three major quantitative trait loci (QTL) on chromosomes 3, 6, and 9 that were consistently detected in at least two of the four populations. Phenotypic variance explained by a single QTL in each population ranged from 3.9% in population 1 to 43.8% in population 2. Joint linkage association mapping across three populations with three biometric models together revealed 16 and 10 main effect QTL for MLN-early and MLN-late, respectively. The QT...Continue Reading

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Citations

Jul 31, 2018·Annual Review of Virology·Margaret G Redinbaugh, Lucy R Stewart
Apr 12, 2020·Plants·Christine NyagaBoddupalli M Prasanna
Oct 3, 2020·Scientific Reports·Nan WangXuecai Zhang
May 18, 2019·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Chelang'at SitonikManje Gowda
Jul 10, 2021·Plant Breeding = Zeitschrift Für Pflanzenzüchtung·Abdoul-Madjidou YacoubouPaterne Agre

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Methods Mentioned

BETA
enzyme-linked immunosorbent assay
ELISA
PCA
genotyping

Software Mentioned

JLAM
SAS
R Development Core Team
TASSEL
BLAST
MEATA
R
QTL IciMapping

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