Discovery of bitriazolyl compounds as novel antiviral candidates for combating the tobacco mosaic virus

Bioorganic & Medicinal Chemistry Letters
Yi XiaLing Peng

Abstract

Bitriazolyl compounds were synthesized and their activity against tobacco mosaic virus was assessed. Two of them showed promising antiviral activity and were more potent than the reference compounds. Moreover, these compounds are predicted not to be carcinogenic or mutagenic based on the prediction systems. Therefore, the bitriazolyl compounds may provide interesting new leads or scaffolds for use in further attempts to screen novel antiviral candidates.

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Citations

Oct 15, 2008·Magnetic Resonance in Chemistry : MRC·Preeti M ChaudharyP R Rajamohanan
Oct 12, 2013·Magnetic Resonance in Chemistry : MRC·Usha D PhalguneP R Rajamohanan
Oct 17, 2018·Plant Methods·Min-Rui WangQiao-Chun Wang
Jul 11, 2014·Organic & Biomolecular Chemistry·Giampiero D'AdamioFrancesca Cardona
Aug 15, 2009·Chemistry : a European Journal·Takashi AbeJean'ne M Shreeve
Aug 14, 2008·Chemical Reviews·Morten Meldal, Christian Wenzel Tornøe

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