Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray

Epigenetics : Official Journal of the DNA Methylation Society
Yi-an ChenRosanna Weksberg

Abstract

DNA methylation, an important type of epigenetic modification in humans, participates in crucial cellular processes, such as embryonic development, X-inactivation, genomic imprinting and chromosome stability. Several platforms have been developed to study genome-wide DNA methylation. Many investigators in the field have chosen the Illumina Infinium HumanMethylation microarray for its ability to reliably assess DNA methylation following sodium bisulfite conversion. Here, we analyzed methylation profiles of 489 adult males and 357 adult females generated by the Infinium HumanMethylation450 microarray. Among the autosomal CpG sites that displayed significant methylation differences between the two sexes, we observed a significant enrichment of cross-reactive probes co-hybridizing to the sex chromosomes with more than 94% sequence identity. This could lead investigators to mistakenly infer the existence of significant autosomal sex-associated methylation. Using sequence identity cutoffs derived from the sex methylation analysis, we concluded that 6% of the array probes can potentially generate spurious signals because of co-hybridization to alternate genomic sequences highly homologous to the intended targets. Additionally, we disc...Continue Reading

References

Feb 13, 1999·Nature Genetics·P A Jones, Peter W Laird
Apr 5, 2002·Genome Research·W James Kent
Apr 14, 2010·PloS One·Jingyu LiuVince Calhoun
Oct 29, 2010·Nature·Gonçalo R AbecasisGil A McVean
Feb 11, 2011·Birth Defects Research. Part A, Clinical and Molecular Teratology·Ronald M AdkinsFridtjof Thomas
Apr 2, 2011·BMC Medical Genetics·Ronald M AdkinsJulia Krushkal
Oct 1, 2009·Epigenomics·Marina BibikovaKevin L Gunderson
Dec 1, 2011·Epigenomics·Sarah DedeurwaerderFrançois Fuks
Mar 17, 2012·International Journal of Epidemiology·Nada BorgholMoshe Szyf

Citations

Aug 31, 2013·Briefings in Bioinformatics·Sarah DedeurwaerderFrançois Fuks
Oct 29, 2013·Human Molecular Genetics·Hongqin XuHuiping Zhang
May 31, 2014·PLoS Genetics·Esther R BerkoJohn M Greally
Sep 17, 2013·PloS One·Dingming WuMichael Q Zhang
Aug 12, 2014·PloS One·Wilfred C de VegaPatrick O McGowan
Feb 15, 2014·The Journal of Steroid Biochemistry and Molecular Biology·Raul A Chavez ValenciaJustine A Ellis
Nov 29, 2013·Epigenomics·Gabrielle A LockettWilfried Karmaus
Jan 28, 2014·Mechanisms of Ageing and Development·Alice C HollyLorna W Harries
Aug 19, 2014·Nature Neuroscience·Philip L De JagerDavid A Bennett
Aug 19, 2014·Nature Neuroscience·Katie LunnonJonathan Mill
Jul 24, 2014·Neuromolecular Medicine·Makoto KinoshitaTetsuro Ohmori
Nov 20, 2014·Breast Cancer Research and Treatment·Gianluca SeveriLaura Baglietto
Feb 18, 2016·Genome Biology·Katie LunnonJonathan Mill
Mar 24, 2015·Expert Review of Molecular Diagnostics·Diego M Marzese, Dave S B Hoon
Jan 12, 2016·Biology·Sergey Kurdyukov, Martyn Bullock
Feb 19, 2016·Epigenetics : Official Journal of the DNA Methylation Society·Jolien RijlaarsdamMarinus H van IJzendoorn
Dec 19, 2015·Epigenetics : Official Journal of the DNA Methylation Society·Min-Ae SongPeter G Shields
Dec 10, 2015·Epigenetics : Official Journal of the DNA Methylation Society·Semira GonsethJoseph Wiemels
Jan 30, 2016·Nature Communications·Andrew E TeschendorffMartin Widschwendter
Feb 2, 2016·Environmental Research·Yan ZhangHermann Brenner
Dec 9, 2015·Human Molecular Genetics·Carolina Soriano-TárragaGENESTROKE Consortium
Dec 10, 2015·Epigenetics : Official Journal of the DNA Methylation Society·Andres CardenasMolly L Kile
Oct 20, 2015·Epigenetics : Official Journal of the DNA Methylation Society·Helen L FisherJonathan Mill
Aug 26, 2015·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Beth WilmotJoel T Nigg
Jan 21, 2016·Epigenetics : Official Journal of the DNA Methylation Society·Ai Ling TehNeerja Karnani
Dec 18, 2015·Nucleic Acids Research·Jeffrey M BhasinAngela H Ting
Dec 1, 2015·Nature Neuroscience·Eilis J HannonJonathan Mill
Oct 1, 2015·Journal of Crohn's & Colitis·Edel McDermottTherese M Murphy
Dec 23, 2015·Nature Communications·Sanaa ChoufaniRosanna Weksberg
Oct 27, 2015·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Nuno R ZilhãoDorret I Boomsma
Dec 2, 2015·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Bart M L BaselmansMeike Bartels
Oct 29, 2015·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Jenny van DongenDorret I Boomsma
Dec 17, 2015·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·S MahurkarL Chang
Apr 22, 2015·Arthritis & Rheumatology·Wouter den HollanderI Meulenbelt
Mar 12, 2016·Epigenetics : Official Journal of the DNA Methylation Society·John K WienckeKarl T Kelsey
Dec 17, 2014·Epigenetics : Official Journal of the DNA Methylation Society·Sara L HillmanDavid J Williams
Apr 30, 2015·Epigenetics : Official Journal of the DNA Methylation Society·Andres CardenasCarmen J Marsit
Aug 4, 2015·Epigenetics : Official Journal of the DNA Methylation Society·Alem S GabrielGordon Strathdee
Mar 25, 2015·Epigenetics : Official Journal of the DNA Methylation Society·C AllardMarie-France Hivert
Jun 4, 2015·Epigenetics : Official Journal of the DNA Methylation Society·Lucas A SalasC M Villanueva
Jun 6, 2015·Epigenetics : Official Journal of the DNA Methylation Society·Arko SenDouglas M Ruden
Dec 9, 2014·Epigenetics : Official Journal of the DNA Methylation Society·Manori AmarasekeraSusan L Prescott
Jan 15, 2015·Epigenetics : Official Journal of the DNA Methylation Society·Shusuke NumataTetsuro Ohmori
Jul 18, 2015·Epigenetics : Official Journal of the DNA Methylation Society·Maya A KappilJia Chen
Aug 21, 2015·Epigenetics : Official Journal of the DNA Methylation Society·Shimrat MamrutAriel Miller
Mar 29, 2016·Epigenetics : Official Journal of the DNA Methylation Society·Kelly M BakulskiM Daniele Fallin
Apr 5, 2016·American Journal of Human Genetics·Bonnie R JoubertStephanie J London
Apr 10, 2015·International Journal of Epidemiology·H Hernandez-VargasMichael N Routledge
Dec 30, 2014·International Journal of Epidemiology·Golareh AghaEric B Loucks
Oct 1, 2015·BMC Genomics·Febilla FernandoCarrie Ris-Stalpers
Apr 9, 2016·Environment International·Samantha L KingsleyGregory A Wellenius
Apr 8, 2016·Nature Communications·Jenny van DongenDorret I Boomsma
Sep 12, 2015·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Ann Zenobia MooreL Ferrucci
Jun 26, 2015·Stem Cells·Galbha DuggalBjörn Heindryckx
Jul 16, 2015·Genes, Chromosomes & Cancer·Ben SchöttkerHermann Brenner
May 20, 2015·Molecular Reproduction and Development·Emily S WanDawn L DeMeo
Jul 1, 2015·Annals of Clinical and Translational Neurology·Lori ChibnikPhilip L De Jager
Oct 31, 2014·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·A K SmithElisabeth B Binder
May 25, 2015·The International Journal of Biochemistry & Cell Biology·Jingyun YangDavid A Bennett
May 9, 2015·European Psychiatry : the Journal of the Association of European Psychiatrists·Aldo Córdova-PalomeraLourdes Fañanás
Jan 15, 2015·Neurobiology of Aging·Katie LunnonMichal Schnaider Beeri
Jul 18, 2015·Genome Biology·Stephanie O M DykeTomi Pastinen
Jan 13, 2015·Epigenetics : Official Journal of the DNA Methylation Society·Nir MelamedRosanna Weksberg
Jun 27, 2015·Biology of Sex Differences·Masatoshi InoshitaTetsuro Ohmori
Jan 28, 2015·Journal of Translational Medicine·Carmen IvorraEmpar Lurbe
Mar 20, 2015·Epigenetics & Chromatin·Netha Ulahannan, John M Greally
May 28, 2015·Clinical Epigenetics·Rebecca V SteenaardAbbas Dehghan
Feb 14, 2015·The Journal of Allergy and Clinical Immunology·David MartinoHealthNuts Study Investigators
Jan 31, 2014·Epigenetics : Official Journal of the DNA Methylation Society·Joana VianaJonathan Mill
Apr 26, 2014·Epigenetics : Official Journal of the DNA Methylation Society·David MartinoSusan L Prescott
Oct 24, 2013·Epigenetics : Official Journal of the DNA Methylation Society·Francisco Sánchez-VegaLaura Elnitski
Mar 26, 2015·Frontiers in Genetics·Jonathan A Heiss, Hermann Brenner
Apr 23, 2016·BMC Bioinformatics·Andrew E TeschendorffMartin Widschwendter
Apr 19, 2015·BMC Bioinformatics·E Andres HousemanCarmen J Marsit
May 6, 2016·Clinical and Translational Allergy·Nicole C M PetrusMarcel M A M Mannens
Apr 30, 2016·Clinical Epigenetics·Michelle L WrightTimothy P York
Sep 30, 2014·PloS One·Dylan AïssiDavid-Alexandre Trégouët
May 7, 2016·Bioinformatics·Alexander J TitusBrock C Christensen
Mar 19, 2014·Lancet·Katherine J DickNilesh J Samani
May 25, 2016·Molecular Psychiatry·E WaltonEdward D Barker
Jun 26, 2015·PLoS Genetics·Qiong Lin, Wolfgang Wagner
Jun 16, 2016·Epigenetics : Official Journal of the DNA Methylation Society·Mia MagnussonSverker Jern
Oct 23, 2015·PLoS Genetics·Roderick C SliekerSusana M Chuva de Sousa Lopes
Jun 29, 2016·Genome Biology·Koen F DekkersBastiaan T Heijmans
Jul 1, 2016·BMC Bioinformatics·E Andres HousemanCarmen J Marsit
Jul 1, 2016·Environmental Science. Processes & Impacts·Jaclyn M GoodrichDana C Dolinoy
Jul 2, 2016·Epigenetics : Official Journal of the DNA Methylation Society·Alison G PaquetteCarmen J Marsit
Aug 27, 2016·Epigenetics : Official Journal of the DNA Methylation Society·Omar AliYi Zhang
Aug 27, 2016·Epigenetics : Official Journal of the DNA Methylation Society·Jarrett D MorrowDawn L DeMeo
Aug 22, 2016·Reproductive Toxicology·Todd M EversonCarmen J Marsit
Oct 1, 2014·Journal of Psychiatry & Neuroscience : JPN·Ken W K LeeZdenka Pausova
Oct 7, 2016·Journal of Psychiatric Research·Annette MilnikVanja Vukojevic
Sep 2, 2016·Seminars in Cell & Developmental Biology·Thomas R PisanicTza-Huei Wang
Sep 20, 2016·Journal of Psychiatric Research·Charlotte A M CecilE Viding
Sep 23, 2016·Genome Biology·Roderick C SliekerBastiaan T Heijmans
Aug 6, 2016·Epigenetics : Official Journal of the DNA Methylation Society·Kristina GervinRobert Lyle
Nov 9, 2016·Clinical Epigenetics·Susan J van DijkBeverly S Muhlhausler
Oct 27, 2015·Epigenetics & Chromatin·Paula SingmannEran Halperin
Jan 10, 2017·Nature·Michael FraserPaul C Boutros
Feb 7, 2017·Epigenetics : Official Journal of the DNA Methylation Society·Xiumei HongXiaobin Wang
Jan 18, 2017·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Julia SteinbergJeremy Mark Wilkinson
Jan 12, 2017·Human Molecular Genetics·Konrad RawlikAlbert Tenesa
Aug 24, 2016·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Nardin SamuelDavid Malkin
Oct 11, 2016·Arthritis & Rheumatology·Brooke RheadLindsey A Criswell
Mar 18, 2017·Nature Communications·Yan ZhangHermann Brenner
Jun 23, 2016·Arthritis & Rheumatology·Michael B ColeLindsey A Criswell
Jun 28, 2016·F1000Research·Jovana MaksimovicAlicia Oshlack
Apr 14, 2017·Scientific Reports·Alex W HewittRichard Saffery
Apr 27, 2017·Nature Communications·Virginie FreytagAndreas Papassotiropoulos
Mar 11, 2015·Human Reproduction·Rocío G UrdinguioAgustin F Fernandez
May 31, 2017·Nature Reviews. Genetics·Tuuli Lappalainen, John M Greally
Feb 21, 2018·Diabetic Medicine : a Journal of the British Diabetic Association·I V YangDana Dabelea
Feb 9, 2018·Genes·Anne Marie SvaneJacob V B Hjelmborg
Oct 14, 2017·Cerebral Cortex·Stefano NardoneEvan Elliott
Mar 27, 2018·International Journal of Cancer. Journal International Du Cancer·Hae Dong WooZdenko Herceg
Mar 29, 2018·Clinical Epigenetics·Flavie PerrierP Ferrari
Apr 6, 2018·Clinical Epigenetics·Yongyue WeiDavid C Christiani
Feb 21, 2018·International Journal of Epidemiology·James R StaleyKate Tilling
Dec 6, 2017·BMC Medicine·Xinyi LinNeerja Karnani
Dec 19, 2017·Translational Psychiatry·Stella IuratoAngelika Erhardt
Jan 10, 2018·Frontiers in Aging Neuroscience·A StarnawskaLene Christiansen
Nov 1, 2017·Molecular Psychiatry·R Karlsson LinnérD J Benjamin
Oct 2, 2014·Genome Research·Agustin F FernandezMario F Fraga
Dec 16, 2017·Scientific Reports·Heba BadraiqDusko Ilic
May 26, 2017·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Rebecca T EmenyKarl-Heinz Ladwig
Jan 5, 2018·Clinical Epigenetics·Anneli C S BolundTorben Sigsgaard
Aug 25, 2017·Epigenetics : Official Journal of the DNA Methylation Society·Charleen D AdamsParveen Bhatti
May 16, 2018·American Journal of Epidemiology·Klodian DhanaAbbas Dehghan
May 18, 2018·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Stephanie ShiauLouise Kuhn
Jun 28, 2018·Epigenetics : Official Journal of the DNA Methylation Society·Boyang ZhangXiaobin Wang
Jun 28, 2016·F1000Research·Jovana MaksimovicAlicia Oshlack
Aug 8, 2018·Scientific Data·Philip L De JagerDavid A Bennett
Oct 14, 2017·American Journal of Physical Anthropology·Christopher J ClukayConnie J Mulligan
Jul 26, 2018·Epigenetics : Official Journal of the DNA Methylation Society·Olivia SolomonNina Holland
Jan 16, 2016·Genome Research·Courtney W HannaWendy P Robinson
Jun 22, 2016·Environmental Health Perspectives·Sarah ReeseStephanie J London
Sep 4, 2018·Epigenetics : Official Journal of the DNA Methylation Society·Anne K BozackMolly L Kile
Oct 2, 2018·Epigenetics : Official Journal of the DNA Methylation Society·Ina ZaimiDominique S Michaud
Aug 30, 2017·Molecular Psychiatry·F W LohoffZachary Kaminsky
Nov 10, 2018·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Charlotte A M CecilE J McCrory
Oct 23, 2018·Epigenetics : Official Journal of the DNA Methylation Society·Juan Jose CarmonaAndrea A Baccarelli
Nov 10, 2018·Epigenetics : Official Journal of the DNA Methylation Society·Jian V HuangAndrea A Baccarelli
Oct 27, 2018·Oral Diseases·Tetsutaro YamaguchiAtsushi Tajima
Nov 20, 2018·PLoS Genetics·Fabien DelahayeFrancine Hughes
Sep 22, 2018·Human Molecular Genetics·Sanaa Choufani3D cohort study group
Jan 10, 2018·Molecular Psychiatry·Riccardo MarioniIan J Deary
May 15, 2015·Epigenetics & Chromatin·Timothy J PetersPeter L Molloy
Jan 25, 2018·European Journal of Human Genetics : EJHG·Izabela M KrzyzewskaPeter Henneman
Feb 1, 2018·Translational Psychiatry·Virginie FreytagAndreas Papassotiropoulos
Feb 13, 2019·Journal of Developmental Origins of Health and Disease·Aya Sasaki, Stephen G Matthews
Feb 13, 2019·Endocrine-related Cancer·Ornella AffinitoMassimo Santoro
Mar 16, 2019·Epigenomics·Jan Maarten CobbenMarcel M A M Mannens
Jan 24, 2018·Proceedings of the National Academy of Sciences of the United States of America·Satoshi YamashitaToshikazu Ushijima
Dec 14, 2017·Epigenetics : Official Journal of the DNA Methylation Society·Anna K KnightA K Smith
Jul 13, 2018·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Pei-Fen KuanPaolo Boffetta
Sep 23, 2017·The Journal of Clinical Endocrinology and Metabolism·Mariana Bisarro Dos ReisSilvia Regina Rogatto
Aug 3, 2018·Development and Psychopathology·Elika GargMavan Study Team
Aug 29, 2013·British Journal of Cancer·Charlotte Wilhelm-BenartziRobert Brown
Jun 10, 2017·Development and Psychopathology·Charlotte A M CecilEdward D Barker
Nov 23, 2017·Development and Psychopathology·Izabela MilaniakSara R Jaffee
Apr 20, 2019·PloS One·Radhika DhingraCavin Ward-Caviness
Apr 27, 2019·PloS One·Danielle A Clarkson-TownsendCarmen J Marsit
Oct 31, 2015·Nature Communications·Jin-Huan WeiJun-Hang Luo
May 10, 2019·Nordic Journal of Psychiatry·Ellen WikeniusMarissa LeBlanc
Jul 10, 2019·Epigenetics : Official Journal of the DNA Methylation Society·Tianxiao HuanDaniel Levy
Jul 23, 2019·PLoS Computational Biology·Yun-Ching Chen, Laura Elnitski
Aug 9, 2019·Neuropsychopharmacology Reports·Yui MurataKazuya Iwamoto
Sep 4, 2019·Translational Psychiatry·A StarnawskaLene Christiansen
Aug 30, 2019·Epigenetics : Official Journal of the DNA Methylation Society·Elizabeth M KennedyCarmen J Marsit
Nov 7, 2018·Scientific Reports·Kirsti KvaløyTurid Lingaas Holmen
Aug 17, 2019·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Mariana L Rodríguez-LópezHumberto Nicolini
Dec 14, 2019·Epigenetics : Official Journal of the DNA Methylation Society·Kathleen CheungLouise N Reynard
Dec 14, 2019·Critical Care Medicine·Alexandra BinnieEpigenetic Profiling in Severe Sepsis (EPSIS) Study of the Canadian Critical Care Translational Biology Group (CCCTBG)
Mar 20, 2018·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Rebecca G SmithKatie Lunnon
Oct 12, 2019·Experimental Dermatology·Viktória KoroknaiMargit Balázs
Feb 26, 2016·Clinical Epigenetics·Daniella KlebanerYan V Sun
Jan 31, 2020·PloS One·Nabila KazmiCaroline L Relton
Oct 28, 2019·Combinatorial Chemistry & High Throughput Screening·Guobo DuBangxian Tan
Jun 4, 2014·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Manori AmarasekeraSusan L Prescott
Feb 23, 2017·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Boris NovakovicRichard Saffery
Mar 11, 2020·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Jesper LundQihua Tan
Apr 3, 2020·Epigenetics : Official Journal of the DNA Methylation Society·Gregory T JonesSally P A McCormick
Apr 25, 2020·Journal of Developmental Origins of Health and Disease·Emilie M HerzogRégine P M Steegers-Theunissen
May 4, 2020·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Maria Elisabeth Koopman-VerhoeffCharlotte A M Cecil
May 4, 2017·Oncotarget·Katarzyna Szarc Vel SzicWim Vanden Berghe
Feb 1, 2018·Oncotarget·Min-Ae SongPeter G Shields
Nov 14, 2015·Oncotarget·Pierre-Benoit AnceyH Hernandez-Vargas
Jan 5, 2020·Clinical Epigenetics·Ting WangWilliam M Grady
Dec 5, 2019·Diabetology & Metabolic Syndrome·Matthew D BarberioMonica J Hubal
Apr 28, 2016·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Benjamin B GreenCarmen J Marsit
Apr 13, 2019·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·Ray O Bahado-SinghUppala Radhakrishna
Jun 4, 2020·Autism Research : Official Journal of the International Society for Autism Research·Sofia StathopoulosColleen O'Ryan
Jun 13, 2019·Nature Communications·Darina CzamaraElisabeth B Binder
Jun 22, 2019·BMC Psychiatry·Yukako NakamuraNorio Ozaki
Jun 26, 2020·Genes·Robert PhilibertMeeshanthini Dogan
Oct 5, 2019·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Fatma Selcen CebeBaha Oral
Sep 22, 2017·Epigenetics : Official Journal of the DNA Methylation Society·Erfan Aref-EshghiBekim Sadikovic
Aug 18, 2020·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Christina A MarkunasJack A Taylor
Oct 16, 2019·Proceedings of the National Academy of Sciences of the United States of America·Lisa M McEwenMichael S Kobor
Sep 23, 2020·Epigenomics·Anna Díez-VillanuevaVictor Moreno
May 13, 2014·G3 : Genes - Genomes - Genetics·Mei-Lyn OngJoanna D Holbrook
Nov 29, 2016·Clinical Epigenetics·Golareh AghaAndrea A Baccarelli
Jan 7, 2017·BMC Genomics·Cheng-Jian XuGerard H Koppelman
Mar 25, 2017·International Journal of Molecular Sciences·Makoto KinoshitaTetsuro Ohmori
Apr 21, 2017·Epigenetics : Official Journal of the DNA Methylation Society·Lucas A SalasBrock C Christensen
Oct 25, 2017·International Journal of Obesity : Journal of the International Association for the Study of Obesity·S J van DijkPeter L Molloy
May 2, 2018·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Gianluca CampanellaMarc Chadeau-Hyam
Sep 7, 2018·Journal of Immunology Research·Srikant AmbatipudiCaroline L Relton
Aug 25, 2018·Clinical Epigenetics·Sungshim L ParkLoïc Le Marchand
Nov 8, 2018·Nature Communications·Javier I J OrozcoDiego M Marzese
Jan 12, 2019·NPJ Science of Learning·Jenny van DongenBIOS Consortium
Jan 11, 2019·Journal of Translational Medicine·Raúl F PérezEmpar Lurbe
Feb 6, 2019·Translational Psychiatry·Susanna RobertsHelen L Fisher
Mar 2, 2019·BMC Genomics·Nerissa L HearnJoanne M Lind
Jan 25, 2019·BMC Ophthalmology·Chung-Ling LiangSuh-Hang H Juo
Apr 16, 2019·Wellcome Open Research·Rosie M WalkerKathryn L Evans
Jun 1, 2019·Environmental Health Perspectives·Olena GruzievaErik Melén
Aug 15, 2019·Clinical Epigenetics·Malgorzata PienkowskaDavid Malkin
Nov 29, 2019·Clinical Epigenetics·Roy LardenoijeDaniel L van den Hove
Nov 23, 2019·Human Genomics·Carlos Ruiz-ArenasJuan R Gonzalez
Dec 22, 2019·Epigenetics & Chromatin·Brenna A LaBarreLaura Elnitski
Oct 31, 2019·Environmental Health : a Global Access Science Source·Karl T KelseyKim Boekelheide
Jan 30, 2020·Epigenetics : Official Journal of the DNA Methylation Society·Rosa H MulderCharlotte A M Cecil
Feb 13, 2020·International Journal of Bipolar Disorders·Ashley L ComesUrs Heilbronner
Jan 16, 2020·Critical Care Medicine·Alexandra BinnieEpigenetic Profiling in Severe Sepsis (EPSIS) Study of the Canadian Critical Care Translational Biology Group (CCCTBG)
Apr 1, 2020·PLoS Genetics·James Y DaiJanet L Stanford
Mar 14, 2020·Scientific Reports·Maite MendiorozJavier García-Campayo
Jun 20, 2015·Epigenomics·Stefanie WeberWalter Doerfler
Feb 13, 2016·Epigenomics·Srikant AmbatipudiZdenko Herceg
Aug 1, 2017·Breast Cancer Research and Treatment·Allyson C EspinalMichael J Higgins
Jan 7, 2018·Journal of Human Genetics·Mihoko ShimadaTsukasa Sasaki
Aug 29, 2017·Obesity·Christopher G Bell
May 31, 2017·Environmental and Molecular Mutagenesis·Olivia SolomonNina Holland
Jul 1, 2018·Journal of Assisted Reproduction and Genetics·Suneeta SenapatiMonica Mainigi
Mar 21, 2018·NPJ Schizophrenia·Daniel L McCartneyKathryn L Evans
Jul 11, 2018·Molecular Autism·Shan V AndrewsChristine Ladd-Acosta
Sep 1, 2018·Nucleic Acids Research·Mehran KarimzadehMichael M Hoffman
Feb 6, 2019·Scientific Reports·Alexandra LahtinenTiina Paunio
Feb 7, 2019·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Philipp JurmeisterDavid Capper
Mar 1, 2019·International Journal of Molecular Sciences·Ting XieSophie Visvikis-Siest
May 10, 2019·Frontiers in Pharmacology·Anil K Giri, Tero Aittokallio
Apr 30, 2019·Frontiers in Genetics·Brigitte ReimannMichelle Plusquin
Aug 31, 2019·Epigenomics·Sailalitha BollepalliMiina Ollikainen
Oct 19, 2019·World Journal of Clinical Cases·Yu-Xia Zhan, Guang-Hua Luo
Dec 13, 2019·American Journal of Medical Genetics. Part C, Seminars in Medical Genetics·Cheryl CytrynbaumRosanna Weksberg
Oct 23, 2019·Journal of Exposure Science & Environmental Epidemiology·Elena ColicinoAndrea A Baccarelli
Apr 14, 2020·Epigenetics : Official Journal of the DNA Methylation Society·Iolanda AgliataH Hernandez-Vargas
Jun 21, 2020·Translational Psychiatry·Paula RoviraMarta Ribasés
May 26, 2020·Epigenetics : Official Journal of the DNA Methylation Society·Timothy P YorkJerome F Strauss
Aug 28, 2020·Translational Psychiatry·Roxann Roberson-NayTimothy P York
Dec 17, 2016·Epigenetics : Official Journal of the DNA Methylation Society·Lingzhen DaiJ D Schwartz
Nov 11, 2015·BMC Genomics·Paul YousefiNina Holland
Dec 17, 2016·Epigenetics & Chromatin·Shan V AndrewsM Daniele Fallin
Sep 20, 2017·BMC Genomics·Helen SpiersJonathan Mill
Oct 24, 2017·Scientific Reports·Tobias EgliAnnette Milnik
Oct 27, 2017·Nature Communications·Shan V AndrewsM Daniele Fallin
Aug 24, 2018·GeroScience·Sangkyu KimS Michal Jazwinski
Nov 23, 2018·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Fu-Ying TianMarie-France Hivert
Jun 10, 2018·Genome Biology·Andrew E TeschendorffKlaus Nordhausen
Mar 20, 2019·Epigenetics : Official Journal of the DNA Methylation Society·Baoshan MaLiming Liang
May 1, 2019·Environmental Health Perspectives·Caitlin G HoweCarrie V Breton
Aug 11, 2019·Epigenetics & Chromatin·Victor YuanWendy P Robinson
Jan 17, 2019·Stem Cell Research & Therapy·Cajsa DavegårdhCharlotte Ling
Oct 25, 2019·Molecular Psychiatry·Christiaan H VinkersMarco P Boks
Jul 20, 2019·Nature Communications·Robert F HillaryRiccardo Marioni
Nov 28, 2019·Scientific Reports·Ellen WikeniusAnders Berglund
Apr 9, 2019·Environmental Epigenetics·Gwen TindulaNina Holland
Jun 15, 2019·Nature Communications·Jun LiuCornelia M van Duijn
Sep 13, 2019·Epigenetics : Official Journal of the DNA Methylation Society·Raúl F PérezAgustin F Fernandez
Feb 3, 2017·Clinical Epigenetics·Mihoko Shimada-SugimotoTsukasa Sasaki
Aug 18, 2017·Clinical Epigenetics·Jacob K KresovichLifang Hou
Nov 16, 2016·Molecular Psychiatry·Chunyu LiuDaniel Levy
Nov 30, 2016·Clinical Epigenetics·René A M DirksHendrik Marks
Mar 2, 2018·Environmental Epigenetics·Kathryn DemanelisLaura S Rozek
Mar 5, 2016·Human Molecular Genetics·Amy RowlattAlbert Tenesa
Jan 13, 2018·Human Molecular Genetics·Weronica E EkÅsa Johansson
Oct 3, 2018·BMC Proceedings·Elise LimChing-Ti Liu
Jan 10, 2018·Genome Biology·Timothy E Van BaakRobert A Waterland
Apr 2, 2019·Epigenetics : Official Journal of the DNA Methylation Society·Sonja NeumeyerJenny Chang-Claude
Dec 21, 2019·Nature Communications·Katharina V SchulzeNeil A Hanchard
May 21, 2019·Journal of Cellular and Molecular Medicine·Yi-Hua LuShu-Feng Lei
May 19, 2019·Breast Cancer Research : BCR·Clara BodelonMontserrat Garcia-Closas
May 5, 2020·Molecular Genetics and Genomics : MGG·Anil K GiriDwaipayan Bharadwaj
Nov 27, 2019·Genome Biology·Christopher G BellVardhman K Rakyan
Jul 21, 2020·BMC Cancer·Maryam Soleimani DodaranAntoine H C van Kampen
Jun 26, 2020·BMC Biology·Yang HanWolfgang Wagner
Dec 7, 2016·Translational Psychiatry·Charlotte A M CecilEdward D Barker
Feb 3, 2017·Epigenetics & Chromatin·Elior RahmaniEran Halperin
Feb 23, 2019·International Journal of Environmental Research and Public Health·Ayoung JeongNicole Probst-Hensch
Mar 13, 2016·American Journal of Physiology. Heart and Circulatory Physiology·Kristen R YeungJoanne M Lind
Feb 21, 2020·Translational Psychiatry·Stefania PolicicchioTherese M Murphy
Dec 18, 2019·Epigenetics : Official Journal of the DNA Methylation Society·Owen M WilkinsBrock C Christensen
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