Discovery of os cordis in the cardiac skeleton of chimpanzees (Pan troglodytes).

Scientific Reports
Sophie MoittiéCatrin Sian Rutland

Abstract

Cardiovascular diseases, especially idiopathic myocardial fibrosis, is one of the most significant causes of morbidity and mortality in captive great apes. This study compared the structure and morphology of 16 hearts from chimpanzees (Pan troglodytes) which were either healthy or affected by myocardial fibrosis using X-ray microtomography. In four hearts, a single, hyperdense structure was detected within the right fibrous trigone of the cardiac skeleton. High resolution scans and histopathology revealed trabecular bones in two cases, hyaline cartilage in another case and a focus of mineralised fibro-cartilaginous metaplasia with endochondral ossification in the last case. Four other animals presented with multiple foci of ectopic calcification within the walls of the great vessels. All hearts affected by marked myocardial fibrosis presented with bone or cartilage formation, and increased collagen levels in tissues adjacent to the bone/cartilage, while unaffected hearts did not present with os cordis or cartilago cordis. The presence of an os cordis has been described in some ruminants, camelids, and otters, but never in great apes. This novel research indicates that an os cordis and cartilago cordis is present in some chimpan...Continue Reading

References

Apr 1, 1968·Annals of Internal Medicine·T N James, E H Drake
Dec 1, 1965·The Anatomical Record·T N James
Oct 1, 1994·The Anatomical Record·B A Young
Aug 6, 1999·Cardiovascular Research·J E Bishop, G Lindahl
Jun 15, 2000·Journal of Anatomy·M EgerbacherS Hauer
Apr 20, 2004·The Journal of the American Academy of Orthopaedic Surgeons·Frederick S KaplanEileen M Shore
Apr 27, 2005·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Benjamin T JohnSumeet S Chugh
Oct 24, 2007·Virchows Archiv : an International Journal of Pathology·Cristina BassoUNKNOWN Association for European Cardiovascular Pathology
Apr 9, 2008·Journal of Medical Primatology·Michael L LammeyMeg M Sleeper
Sep 2, 2008·Physics in Medicine and Biology·C T BadeaG A Johnson
Sep 8, 2009·Trends in Molecular Medicine·Veerle Persy, Patrick D'Haese
Feb 20, 2010·Journal of Comparative Pathology·K MatsudaH Taniyama
Mar 6, 2010·Journal of Veterinary Internal Medicine·G WessK Hartmann
Jul 14, 2010·Journal of the American College of Cardiology·Christine JellisThomas H Marwick
Sep 8, 2010·Bone·Michael DoubeSandra J Shefelbine
Jan 31, 2012·Journal of Clinical Pathology·Mary N Sheppard
Aug 30, 2012·Nature Methods·Caroline A SchneiderKevin W Eliceiri
Aug 28, 2013·Anatomical Science International·Serkan ErdoğanWilliam Pérez
Apr 5, 2014·Journal of the American Veterinary Medical Association·Meg M SleeperMichael L Lammey
Aug 30, 2014·PloS One·Timothy D ButtersHenggui Zhang
Sep 6, 2014·BMC Veterinary Research·Hiroshi SasaiYuki Izumi
Feb 18, 2015·Stem Cell Research & Therapy·Joel D BoerckelEben Alsberg
Jun 5, 2015·Journal of the American Veterinary Medical Association·Hiroshi SasaiJyoji Yamate
Jul 3, 2015·The Journal of Bone and Joint Surgery. American Volume·Kavitha RanganathanBenjamin Levi
Oct 4, 2016·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Victoria J StrongKate White
Feb 6, 2017·European Journal of Heart Failure·Mariann GyöngyösiFaiez Zannad
Aug 19, 2017·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Farhood SaremiRobert H Anderson
Oct 24, 2019·Veterinary Pathology·Victoria StrongKerstin Baiker

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Methods Mentioned

BETA
biopsies
X-ray
dissection

Software Mentioned

datos
VGStudioMax
ImageJ
Image Pro
BoneJ

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