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Discovery of transcription factors and regulatory regions driving in vivo tumor development by ATAC-seq and FAIRE-seq open chromatin profiling

PLoS Genetics

Feb 1, 2015

Kristofer DavieStein Aerts

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Abstract

Genomic enhancers regulate spatio-temporal gene expression by recruiting specific combinations of transcription factors (TFs). When TFs are bound to active regulatory regions, they displace canonical nucleosomes, making these regions biochemically detectable as nucleosome-depleted regio...read more

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Enhancer brand
Sodium Chloride
Gene Expression
Immunoprecipitation
Complex (molecular entity)
Mutant
Ligands
Phenols
JAK-STAT Cascade
JUN gene
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Discovery of transcription factors and regulatory regions driving in vivo tumor development by ATAC-seq and FAIRE-seq open chromatin profiling

PLoS Genetics

Feb 1, 2015

Kristofer DavieStein Aerts

PMID: 25679813

DOI: 10.1371/journal.pgen.1004994

Abstract

Genomic enhancers regulate spatio-temporal gene expression by recruiting specific combinations of transcription factors (TFs). When TFs are bound to active regulatory regions, they displace canonical nucleosomes, making these regions biochemically detectable as nucleosome-depleted regio...read more

Mentioned in this Paper

Enhancer brand
Sodium Chloride
Gene Expression
Immunoprecipitation
Complex (molecular entity)
13
1
455

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References70
  • Citations23
12345...
  • References70
  • Citations23
123

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