Discrepancies in cancer mortality estimates

Archives of Medical Research
Ernesto Goldman, James L Fisher

Abstract

Progress against cancer-associated mortality could be estimated by mortality rates. However, population-based measures may not be comparable to trends across time based on individual cases followed over time. For two leading cancer types (colorectal and lung and bronchus), the following were calculated from the Surveillance, Epidemiology, and End Results (SEER) Program survival matrix output: probability of death (PD) as the relative cumulative deaths in a cohort of cancer patients at 12-month intervals after the year of diagnosis, 5-year survival probability, and median survival time. Annual age-adjusted U.S. mortality rates were obtained from the National Center for Health Statistics (NCHS). Colorectal cancer PD 5-year (patients having survived up to 5 years after diagnosis) decreased 4.3% from 1985-1997, in contrast to a 20% decrease in the mortality rate during the same period. The mortality rate for lung and bronchus cancer sharply increased between 1973 and 1991 and was followed by a clear downward trend of 2.5% from 1991-1997, while its PD 5-year decreased by only 0.79%. PD for specific cohorts at yearly intervals did not improve across time at comparable intervals; however, the mortality rate was clearly reduced for bot...Continue Reading

References

Jun 24, 2000·JAMA : the Journal of the American Medical Association·H G WelchS Woloshin

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Citations

Jan 31, 2008·JAMA : the Journal of the American Medical Association·Aaron J SchetterCurtis C Harris
Mar 12, 2013·International Journal of Colorectal Disease·Hui LiuChuanxin Wang
May 30, 2015·International Journal of Molecular Sciences·Zewu LiChuanxin Wang
Aug 26, 2017·Biomarkers in Medicine·Xingwei GuGuodong Zhao
Jan 29, 2013·European Journal of Gastroenterology & Hepatology·Zhi-Gang XiaoZhong-Cheng Huang
May 15, 2013·Molecular and Cellular Biochemistry·Ge YuJianqiang Tang

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