Discrepancies in the evaluation of the safety of the human papillomavirus vaccine

Memórias do Instituto Oswaldo Cruz
Jorge L Cervantes, Amy Hoanganh Doan

Abstract

Despite being more than ten years since its introduction, global acceptance to the human papillomavirus (HPV) vaccine is still low. The immunogenetic background of the host, and HPV antigen recognition, are important in natural HPV infection, and should be taken into account in the understanding of adverse autoimmune reactions by the HPV vaccine in certain groups. There is no doubt of the benefit of vaccines in the reduction of the incidence of infectious diseases, and in the case of HPV, the prevention of persistent infection that would lead to cervical cancer. Side-effects, however, should be closely monitored and reported without any bias, to ensure that the benefits of vaccines outweigh the risks of adverse reactions. In this article we bring the attention on certain adverse effects of the vaccine against HPV that have not been well studied as they are not well defined. We also compare the different approaches on HPV vaccine policies regarding its adverse reactions in countries like Japan and Colombia, vs. the recommendations issued by the WHO.

References

Jul 19, 2003·Revista Do Instituto De Medicina Tropical De São Paulo·Jorge CervantesShunro Sonoda
Jan 9, 2010·The American Journal of Medicine·Don L Goldenberg
Oct 12, 2011·The Journal of Infectious Diseases·Jorge L Cervantes
Jan 12, 2012·Lupus·H F SoldevillaS V Navarra
Apr 8, 2014·Case Reports in Ophthalmology·Ken OginoNagahisa Yoshimura
Dec 24, 2014·The Lancet Oncology·Tony Kirby
Sep 12, 2015·Clinical Rheumatology·Manuel Martínez-LavínPaola Reyes-Loyola
Oct 18, 2015·Journal of the American Academy of Dermatology·Nancy S HandlerRobert A Schwartz
Jan 19, 2016·EBioMedicine·Cindy M Weinbaum, Maria Cano
Feb 3, 2016·Human Vaccines & Immunotherapeutics·Joseph G SkeateW Martin Kast
Apr 1, 2016·Human Vaccines & Immunotherapeutics·Julianne GeeLauri E Markowitz
Sep 7, 2016·Immunologic Research·Osamu HottaUNKNOWN Japanese Focal Inflammation Research Group
Jun 10, 2017·Vaccine·UNKNOWN World Health Organization. Electronic address: sageexecsec@who.int
Jun 11, 2017·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Dimitri PoddigheBeniaminoi Palmieri

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.