PMID: 19915745Nov 17, 2009Paper

Discrepancy variation of dinucleotide microsatellite repeats in eukaryotic genomes

Biological Research
Huan GaoFei Yu

Abstract

To address whether there are differences of variation among repeat motif types and among taxonomic groups, we present here an analysis of variation and correlation of dinucleotide microsatellite repeats in eukaryotic genomes. Ten taxonomic groups were compared, those being primates, mammalia (excluding primates and rodentia), rodentia, birds, fish, amphibians and reptiles, insects, molluscs, plants and fungi, respectively. The data used in the analysis is from the literature published in the Journal of Molecular Ecology Notes. Analysis of variation reveals that there are no significant differences between AC and AG repeat motif types. Moreover, the number of alleles correlates positively with the copy number in both AG and AC repeats. Similar conclusions can be obtained from each taxonomic group. These results strongly suggest that the increase of SSR variation is almost linear with the increase of the copy number of each repeat motif. As well, the results suggest that the variability of SSR in the genomes of low-ranking species seem to be more than that of high-ranking species, excluding primates and fungi.

Citations

Mar 17, 2012·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Mulatu GeletaTomas Bryngelsson
Jul 19, 2011·Molecular Genetics and Genomics : MGG·Caihua GaoJiana Li

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