Discrete start sites for DNA synthesis in the yeast ARS1 origin

Science
A K Bielinsky, S A Gerbi

Abstract

Sites of DNA synthesis initiation have been detected at the nucleotide level in a yeast origin of bidirectional replication with the use of replication initiation point mapping. The ARS1 origin of Saccharomyces cerevisiae showed a transition from discontinuous to continuous DNA synthesis in an 18-base pair region (nucleotides 828 to 845) from within element B1 toward B2, adjacent to the binding site for the origin recognition complex, the putative initiator protein.

References

Sep 1, 1977·Cell·A B Blumenthal, E J Clark
Nov 3, 1989·Science·R A LaskeyJ J Blow
Dec 1, 1988·Microbiological Reviews·C S Newlon
Apr 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·J F Diffley, B Stillman
Jan 1, 1993·Annual Review of Biochemistry·M L DePamphilis
Sep 1, 1997·Molecular and Cellular Biology·S Lin, D Kowalski

❮ Previous
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Citations

Mar 10, 1999·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·M L DePamphilis
Jun 22, 2000·Journal of Cellular Biochemistry·L TaoG Price
Oct 28, 2009·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Joyce L HamlinPieter A Dijkwel
Aug 5, 1998·Biochimica Et Biophysica Acta·S E Kearsey, K Labib
Jun 26, 1998·Current Opinion in Cell Biology·P Pasero, S M Gasser
Jan 23, 1999·Current Opinion in Cell Biology·J Leatherwood
Jun 4, 1998·Current Opinion in Genetics & Development·D M Gilbert
Mar 11, 1999·Current Opinion in Genetics & Development·A D Donaldson, J J Blow
Dec 20, 2002·Journal of Structural Biology·Susan A GerbiJohn M Waggener
Sep 28, 2000·Current Opinion in Chemical Biology·M J Davey, M O'Donnell
Mar 16, 2012·Nature·Duncan J Smith, Iestyn Whitehouse
Apr 11, 2006·Nature Biotechnology·Haiqing FuMirit I Aladjem
Jul 13, 2004·Nature Cell Biology·Etienne DanisMarcel Méchali
Oct 18, 2008·Nature Protocols·Julia Romero, Hoyun Lee
Feb 17, 1999·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·M FujitaC Obuse
Oct 6, 1997·Proceedings of the National Academy of Sciences of the United States of America·J F Theis, C S Newlon
Apr 25, 2000·Nucleic Acids Research·D SantamaríaJ B Schvartzman
Aug 9, 2005·Nucleic Acids Research·Alla BuzinaJames Ellis
Feb 5, 2008·Genes & Development·María Gómez, Francisco Antequera
Aug 5, 2011·Genome Research·Melvenia M MartinMirit I Aladjem
Mar 9, 2002·Journal of Virology·Peter C AngelettiPaul F Lambert
Jun 25, 2008·Molecular and Cellular Biology·Slavica StanojcicMarcel Mechali
Jun 20, 2006·Molecular and Cellular Biology·Sapna Das-BradooAnja-Katrin Bielinsky
Jul 13, 2000·Molecular and Cellular Biology·M GruberJ M Sogo
Nov 26, 2002·Molecular and Cellular Biology·Victoria V LunyakSusan A Gerbi
Sep 16, 2003·Molecular and Cellular Biology·Kevin J Harvey, John Newport
Oct 16, 2003·Molecular and Cellular Biology·Julie L CallahanCatherine H Freudenreich

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