PMID: 9190291Feb 1, 1997Paper

Discriminating among the discriminator bases of tRNAs

Chemistry & Biology
Y M Hou

Abstract

Aminoacyl-tRNA synthetases must select their specific tRNAs from the 20 structurally similar tRNAs present in a cell. The discriminator base, at position 73 of the tRNA, is important for this selection but its effects on aminoacylation are variable depending on context. Recent structural studies provide insight into this variability.

References

May 11, 1992·Nucleic Acids Research·K TamuraM Shimizu
Dec 15, 1992·Biochemical and Biophysical Research Communications·N NamekiM Shimizu
Apr 15, 1992·Biochemical and Biophysical Research Communications·T HasegawaM Shimizu
Dec 11, 1991·Nucleic Acids Research·H HimenoM Shimizu
Jun 14, 1991·Biochemical and Biophysical Research Communications·K TamuraM Shimizu
Dec 11, 1990·Nucleic Acids Research·H HimenoM Shimizu
Oct 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·D M CrothersG Söll
Jan 11, 1995·Nucleic Acids Research·H LiuK Musier-Forsyth
Feb 11, 1995·Nucleic Acids Research·N NamekiH Himeno
Nov 22, 1994·Proceedings of the National Academy of Sciences of the United States of America·E V PuglisiU L RajBhandary
Jul 27, 1993·Biochemistry·G A Komatsoulis, J Abelson
Jul 9, 1996·Proceedings of the National Academy of Sciences of the United States of America·M IbbaD Söll

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Citations

Apr 4, 2001·The EMBO Journal·H SaitoH Suga
Nov 4, 1998·Nucleic Acids Research·R GiegéC Florentz
Aug 31, 2000·Annual Review of Biochemistry·M Ibba, D Soll
May 11, 2015·Nucleic Acids Research·Sandra WendeMario Mörl
Feb 6, 2017·Biochimica Et Biophysica Acta. General Subjects·Kyle S HoffmanChristopher J Brandl
Jul 27, 2007·Chembiochem : a European Journal of Chemical Biology·Zhaohui YanAnne M Baranger
Aug 14, 2019·RNA Biology·Matthew D BergChristopher J Brandl
Sep 6, 2019·Genetics·Matthew D BergChristopher J Brandl
Dec 22, 1999·The Journal of Biological Chemistry·A E FischerK Musier-Forsyth
Mar 29, 2000·Biopolymers·P J Beuning, K Musier-Forsyth
Jul 29, 2004·The Journal of Biological Chemistry·Jie JiaYou-Xin Jin
Nov 1, 2019·Genetics·Matthew D BergChristopher J Brandl
Apr 4, 2021·RNA·Conner J LangebergJeffrey S Kieft

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